Detectable clonal mosaicism and its relationship to aging and cancer
Identifieur interne : 005412 ( Main/Exploration ); précédent : 005411; suivant : 005413Detectable clonal mosaicism and its relationship to aging and cancer
Auteurs : Kevin B. Jacobs [États-Unis] ; Meredith Yeager [États-Unis] ; Weiyin Zhou [États-Unis] ; Sholom Wacholder [États-Unis] ; Zhaoming Wang [États-Unis] ; Benjamin Rodriguez-Santiago [Espagne] ; Amy Hutchinson [États-Unis] ; Xiang Deng [États-Unis] ; Chenwei Liu [États-Unis] ; Marie-Josephe Horner [États-Unis] ; Michael Cullen [États-Unis] ; Caroline G. Epstein [États-Unis] ; Laurie Burdett [États-Unis] ; Michael C. Dean [États-Unis] ; Nilanjan Chatterjee [États-Unis] ; Joshua Sampson [États-Unis] ; Charles C. Chung [États-Unis] ; Joseph Kovaks [États-Unis] ; Susan M. Gapstur [États-Unis] ; Victoria L. Stevens [États-Unis] ; Lauren T. Teras [États-Unis] ; Mia M. Gaudet [États-Unis] ; Demetrius Albanes [États-Unis] ; Stephanie J. Weinstein [États-Unis] ; Jarmo Virtamo [Finlande] ; Philip R. Taylor [États-Unis] ; Neal D. Freedman [États-Unis] ; Christian C. Abnet [États-Unis] ; Alisa M. Goldstein [États-Unis] ; Nan Hu [États-Unis] ; Kai Yu [États-Unis] ; Jian-Min Yuan [États-Unis] ; Linda Liao [États-Unis] ; Ti Ding [République populaire de Chine] ; You-Lin Qiao [République populaire de Chine] ; Yu-Tang Gao [République populaire de Chine] ; Woon-Puay Koh [Singapour] ; Yong-Bing Xiang [République populaire de Chine] ; Ze-Zhong Tang [République populaire de Chine] ; Jin-Hu Fan [République populaire de Chine] ; Melinda C. Aldrich [États-Unis] ; Christopher Amos [États-Unis] ; William J. Blot [États-Unis] ; Cathryn H. Bock [États-Unis] ; Elizabeth M. Gillanders [États-Unis] ; Curtis C. Harris [États-Unis] ; Christopher A. Haiman [États-Unis] ; Brian E. Henderson [États-Unis] ; Laurence N. Kolonel [États-Unis] ; Loic Le Marchand [États-Unis] ; Lorna H. Mcneill [États-Unis] ; Benjamin A. Rybicki [États-Unis] ; Ann G. Schwartz [États-Unis] ; Lisa B. Signorello [États-Unis] ; Margaret R. Spitz [États-Unis] ; John K. Wiencke [États-Unis] ; Margaret Wrensch [États-Unis] ; Xifeng Wu [États-Unis] ; Krista A. Zanetti [États-Unis] ; Regina G. Ziegler [États-Unis] ; Jonine D. Figueroa [États-Unis] ; Montserrat Garcia-Closas [États-Unis, Royaume-Uni] ; Nuria Malats [Espagne] ; Gaelle Marenne [Espagne] ; Ludmila Prokunina-Olsson [États-Unis] ; Dalsu Baris [États-Unis] ; Molly Schwenn [États-Unis] ; Alison Johnson [États-Unis] ; Maria Teresa Landi [États-Unis] ; Lynn Goldin [États-Unis] ; Dario Consonni [Italie] ; Pier Alberto Bertazzi [Italie] ; Melissa Rotunno [États-Unis] ; Preetha Rajaraman [États-Unis] ; Ulrika Andersson [Suède] ; Laura E Beane Freeman [États-Unis] ; Christine D. Berg [États-Unis] ; Julie E. Buring [États-Unis] ; Mary A. Butler [États-Unis] ; Tania Carreon [États-Unis] ; Maria Feychting [Suède] ; Anders Ahlbom [Suède] ; J Michael Gaziano [États-Unis] ; Graham G. Giles [Australie] ; Goran Hallmans [Suède] ; Susan E. Hankinson [États-Unis] ; Patricia Hartge [États-Unis] ; Roger Henriksson [Suède] ; Peter D. Inskip [États-Unis] ; Christoffer Johansen [Danemark] ; Annelie Landgren [États-Unis] ; Roberta Mckean-Cowdin [États-Unis] ; Dominique S. Michaud [Royaume-Uni, États-Unis] ; Beatrice S. Melin [Suède] ; Ulrike Peters [États-Unis] ; Avima M. Ruder [États-Unis] ; Howard D. Sesso [États-Unis] ; Gianluca Severi [Australie] ; Xiao-Ou Shu [États-Unis] ; Kala Visvanathan [États-Unis] ; Emily White [États-Unis] ; Alicja Wolk [Suède] ; Anne Zeleniuch-Jacquotte [États-Unis] ; Wei Zheng [États-Unis] ; Debra T. Silverman [États-Unis] ; Manolis Kogevinas [Grèce, Espagne] ; Juan R. Gonzalez [Espagne] ; Olaya Villa [Espagne] ; Donghui Li [États-Unis] ; Eric J. Duell [Espagne] ; Harvey A. Risch [États-Unis] ; Sara H. Olson [États-Unis] ; Charles Kooperberg [États-Unis] ; Brian M. Wolpin [États-Unis] ; Li Jiao [États-Unis] ; Manal Hassan [États-Unis] ; William Wheeler [États-Unis] ; Alan A. Arslan [États-Unis] ; H. Bas Bueno-De-Mesquita [Pays-Bas] ; Charles S. Fuchs [États-Unis] ; Steven Gallinger [Canada] ; Myron D. Gross [États-Unis] ; Elizabeth A. Holly [États-Unis] ; Alison P. Klein [États-Unis] ; Andrea Lacroix [États-Unis] ; Margaret T. Mandelson [États-Unis] ; Gloria Petersen [États-Unis] ; Marie-Christine Boutron-Ruault [France] ; Paige M. Bracci [États-Unis] ; Federico Canzian [Allemagne] ; Kenneth Chang [États-Unis] ; Michelle Cotterchio [Canada] ; Edward L. Giovannucci [États-Unis] ; Michael Goggins [États-Unis] ; Judith A Hoffman Bolton [États-Unis] ; Mazda Jenab [France] ; Kay-Tee Khaw [Royaume-Uni] ; Vittorio Krogh [Italie] ; Robert C. Kurtz [États-Unis] ; Robert R. Mcwilliams [États-Unis] ; Julie B. Mendelsohn [États-Unis] ; Kari G. Rabe [États-Unis] ; Elio Riboli [Royaume-Uni] ; Anne Tj Nneland [Danemark] ; Geoffrey S. Tobias [États-Unis] ; Dimitrios Trichopoulos [États-Unis, Grèce] ; Joanne W. Elena [États-Unis] ; Herbert Yu [États-Unis] ; Laufey Amundadottir [États-Unis] ; Rachael Z. Stolzenberg-Solomon [États-Unis] ; Peter Kraft [États-Unis] ; Fredrick Schumacher [États-Unis] ; Daniel Stram [États-Unis] ; Sharon A. Savage [États-Unis] ; Lisa Mirabello [États-Unis] ; Irene L. Andrulis [Canada] ; Jay S. Wunder [Canada] ; Ana Pati O García [Espagne] ; Luis Sierrasesúmaga [Espagne] ; Donald A. Barkauskas [États-Unis] ; Richard G. Gorlick [États-Unis] ; Mark Purdue [États-Unis] ; Wong-Ho Chow [États-Unis] ; Lee E. Moore [États-Unis] ; Kendra L. Schwartz [États-Unis] ; Faith G. Davis [États-Unis] ; Ann W. Hsing [États-Unis] ; Sonja I. Berndt [États-Unis] ; Amanda Black [États-Unis] ; Nicolas Wentzensen [États-Unis] ; Louise A. Brinton [États-Unis] ; Jolanta Lissowska [Pologne] ; Beata Peplonska [Pologne] ; Katherine A. Mcglynn [États-Unis] ; Michael B. Cook [États-Unis] ; Barry I. Graubard [États-Unis] ; Christian P. Kratz [États-Unis, Allemagne] ; Mark H. Greene [États-Unis] ; Ralph L. Erickson [États-Unis] ; David J. Hunter [États-Unis] ; Gilles Thomas [États-Unis] ; Robert N. Hoover [États-Unis] ; Francisco X. Real [Espagne] ; Joseph F. Fraumeni [États-Unis] ; Neil E. Caporaso [États-Unis] ; Margaret Tucker [États-Unis] ; Nathaniel Rothman [États-Unis] ; Luis A. Pérez-Jurado [Espagne] ; Stephen J. Chanock [États-Unis]Source :
- Nature genetics [ 1061-4036 ] ; 2012.
Abstract
In an analysis of 31,717 cancer cases and 26,136 cancer-free controls drawn from 13 genome-wide association studies (GWAS), we observed large chromosomal abnormalities in a subset of clones from DNA obtained from blood or buccal samples. Mosaic chromosomal abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of size >2 Mb were observed in autosomes of 517 individuals (0.89%) with abnormal cell proportions between 7% and 95%. In cancer-free individuals, the frequency increased with age; 0.23% under 50 and 1.91% between 75 and 79 (p=4.8×10−8). Mosaic abnormalities were more frequent in individuals with solid-tumors (0.97% versus 0.74% in cancer-free individuals, OR=1.25, p=0.016), with a stronger association for cases who had DNA collected prior to diagnosis or treatment (OR=1.45, p=0.0005). Detectable clonal mosaicism was common in individuals for whom DNA was collected at least one year prior to diagnosis of leukemia compared to cancer-free individuals (OR=35.4, p=3.8×10−11). These findings underscore the importance of the role and time-dependent nature of somatic events in the etiology of cancer and other late-onset diseases.
Url:
DOI: 10.1038/ng.2270
PubMed: 22561519
PubMed Central: 3372921
Affiliations:
- Allemagne, Australie, Canada, Danemark, Espagne, Finlande, France, Grèce, Italie, Pays-Bas, Pologne, Royaume-Uni, République populaire de Chine, Singapour, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Attique (région), Auvergne-Rhône-Alpes, Bade-Wurtemberg, Basse-Saxe, Californie, Catalogne, Communauté de Madrid, Connecticut, District de Karlsruhe, Grand Londres, Géorgie (États-Unis), Hovedstaden, Illinois, Lombardie, Maine (État), Maryland, Massachusetts, Michigan, Minnesota, Ohio, Ontario, Pennsylvanie, Rhode Island, Rhône-Alpes, Svealand, Tennessee, Texas, Utrecht (province), Vermont, Victoria (État), Washington (État), État de New York
- Athènes, Barcelone, Cambridge, Chicago, Copenhague, Hanovre, Heidelberg, Londres, Lyon, Madrid, Melbourne, Milan, Providence (Rhode Island), Pékin, Seattle, Stockholm, Toronto, Utrecht
- Université Brown, Université Pompeu Fabra, Université de Cambridge, Université de Melbourne, Université de Toronto, Université de Washington, Université de l'Illinois à Chicago, Université nationale de Singapour
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Chung</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kovaks, Joseph" sort="Kovaks, Joseph" uniqKey="Kovaks J" first="Joseph" last="Kovaks">Joseph Kovaks</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Teras, Lauren T" sort="Teras, Lauren T" uniqKey="Teras L" first="Lauren T" last="Teras">Lauren T. Teras</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M" last="Gaudet">Mia M. Gaudet</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Weinstein, Stephanie J" sort="Weinstein, Stephanie J" uniqKey="Weinstein S" first="Stephanie J" last="Weinstein">Stephanie J. Weinstein</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation wicri:level="1"><nlm:aff id="A8"> Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea> Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Abnet, Christian C" sort="Abnet, Christian C" uniqKey="Abnet C" first="Christian C" last="Abnet">Christian C. Abnet</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Goldstein, Alisa M" sort="Goldstein, Alisa M" uniqKey="Goldstein A" first="Alisa M" last="Goldstein">Alisa M. Goldstein</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hu, Nan" sort="Hu, Nan" uniqKey="Hu N" first="Nan" last="Hu">Nan Hu</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yu, Kai" sort="Yu, Kai" uniqKey="Yu K" first="Kai" last="Yu">Kai Yu</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yuan, Jian Min" sort="Yuan, Jian Min" uniqKey="Yuan J" first="Jian-Min" last="Yuan">Jian-Min Yuan</name><affiliation wicri:level="2"><nlm:aff id="A9"> Department of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10"> University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Liao, Linda" sort="Liao, Linda" uniqKey="Liao L" first="Linda" last="Liao">Linda Liao</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ding, Ti" sort="Ding, Ti" uniqKey="Ding T" first="Ti" last="Ding">Ti Ding</name><affiliation wicri:level="1"><nlm:aff id="A11"> Shanxi Cancer Hospital, Taiyuan, Shanxi, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanxi Cancer Hospital, Taiyuan, Shanxi</wicri:regionArea><wicri:noRegion>Shanxi</wicri:noRegion></affiliation></author><author><name sortKey="Qiao, You Lin" sort="Qiao, You Lin" uniqKey="Qiao Y" first="You-Lin" last="Qiao">You-Lin Qiao</name><affiliation wicri:level="3"><nlm:aff id="A12"> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation wicri:level="1"><nlm:aff id="A13"> Shanghai Cancer Institute, Shanghai, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanghai Cancer Institute, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Woon Puay" sort="Koh, Woon Puay" uniqKey="Koh W" first="Woon-Puay" last="Koh">Woon-Puay Koh</name><affiliation wicri:level="4"><nlm:aff id="A14"> Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea> Saw Swee Hock School of Public Health, National University of Singapore</wicri:regionArea><orgName type="university">Université nationale de Singapour</orgName></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation wicri:level="1"><nlm:aff id="A13"> Shanghai Cancer Institute, Shanghai, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanghai Cancer Institute, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Tang, Ze Zhong" sort="Tang, Ze Zhong" uniqKey="Tang Z" first="Ze-Zhong" last="Tang">Ze-Zhong Tang</name><affiliation wicri:level="1"><nlm:aff id="A11"> Shanxi Cancer Hospital, Taiyuan, Shanxi, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanxi Cancer Hospital, Taiyuan, Shanxi</wicri:regionArea><wicri:noRegion>Shanxi</wicri:noRegion></affiliation></author><author><name sortKey="Fan, Jin Hu" sort="Fan, Jin Hu" uniqKey="Fan J" first="Jin-Hu" last="Fan">Jin-Hu Fan</name><affiliation wicri:level="3"><nlm:aff id="A12"> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><affiliation wicri:level="2"><nlm:aff id="A15"> Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Amos, Christopher" sort="Amos, Christopher" uniqKey="Amos C" first="Christopher" last="Amos">Christopher Amos</name><affiliation wicri:level="2"><nlm:aff id="A17"> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Blot, William J" sort="Blot, William J" uniqKey="Blot W" first="William J" last="Blot">William J. Blot</name><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A18"> International Epidemiology Institute, Rockville, Maryland 20850, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> International Epidemiology Institute, Rockville, Maryland 20850</wicri:regionArea><wicri:noRegion>Maryland 20850</wicri:noRegion></affiliation></author><author><name sortKey="Bock, Cathryn H" sort="Bock, Cathryn H" uniqKey="Bock C" first="Cathryn H" last="Bock">Cathryn H. Bock</name><affiliation wicri:level="2"><nlm:aff id="A19"> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20"> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Gillanders, Elizabeth M" sort="Gillanders, Elizabeth M" uniqKey="Gillanders E" first="Elizabeth M" last="Gillanders">Elizabeth M. Gillanders</name><affiliation wicri:level="1"><nlm:aff id="A21"> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Harris, Curtis C" sort="Harris, Curtis C" uniqKey="Harris C" first="Curtis C" last="Harris">Curtis C. Harris</name><affiliation wicri:level="1"><nlm:aff id="A22"> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N" last="Kolonel">Laurence N. Kolonel</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Mcneill, Lorna H" sort="Mcneill, Lorna H" uniqKey="Mcneill L" first="Lorna H" last="Mcneill">Lorna H. Mcneill</name><affiliation wicri:level="1"><nlm:aff id="A25"> Department of Health Disparities Research, Division of Office of the Vice-President, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas , USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Disparities Research, Division of Office of the Vice-President, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas </wicri:regionArea><wicri:noRegion>Texas </wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A26"> Center for Community Engaged Translational Research , Duncan Family Institute, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Center for Community Engaged Translational Research , Duncan Family Institute, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Rybicki, Benjamin A" sort="Rybicki, Benjamin A" uniqKey="Rybicki B" first="Benjamin A" last="Rybicki">Benjamin A. Rybicki</name><affiliation wicri:level="1"><nlm:aff id="A27"> Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan 48202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan 48202</wicri:regionArea><wicri:noRegion>Michigan 48202</wicri:noRegion></affiliation></author><author><name sortKey="Schwartz, Ann G" sort="Schwartz, Ann G" uniqKey="Schwartz A" first="Ann G" last="Schwartz">Ann G. Schwartz</name><affiliation wicri:level="2"><nlm:aff id="A19"> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20"> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Signorello, Lisa B" sort="Signorello, Lisa B" uniqKey="Signorello L" first="Lisa B" last="Signorello">Lisa B. Signorello</name><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A18"> International Epidemiology Institute, Rockville, Maryland 20850, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> International Epidemiology Institute, Rockville, Maryland 20850</wicri:regionArea><wicri:noRegion>Maryland 20850</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Spitz, Margaret R" sort="Spitz, Margaret R" uniqKey="Spitz M" first="Margaret R" last="Spitz">Margaret R. Spitz</name><affiliation wicri:level="2"><nlm:aff id="A29"> Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Wiencke, John K" sort="Wiencke, John K" uniqKey="Wiencke J" first="John K" last="Wiencke">John K. Wiencke</name><affiliation wicri:level="1"><nlm:aff id="A30"> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158</wicri:regionArea><wicri:noRegion>California 94158</wicri:noRegion></affiliation></author><author><name sortKey="Wrensch, Margaret" sort="Wrensch, Margaret" uniqKey="Wrensch M" first="Margaret" last="Wrensch">Margaret Wrensch</name><affiliation wicri:level="1"><nlm:aff id="A30"> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158</wicri:regionArea><wicri:noRegion>California 94158</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><affiliation wicri:level="2"><nlm:aff id="A17"> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Zanetti, Krista A" sort="Zanetti, Krista A" uniqKey="Zanetti K" first="Krista A" last="Zanetti">Krista A. Zanetti</name><affiliation wicri:level="1"><nlm:aff id="A21"> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A22"> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Ziegler, Regina G" sort="Ziegler, Regina G" uniqKey="Ziegler R" first="Regina G" last="Ziegler">Regina G. Ziegler</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D" last="Figueroa">Jonine D. Figueroa</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A31"> Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Genetics and Epidemiology, Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Malats, Nuria" sort="Malats, Nuria" uniqKey="Malats N" first="Nuria" last="Malats">Nuria Malats</name><affiliation wicri:level="3"><nlm:aff id="A32"> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Marenne, Gaelle" sort="Marenne, Gaelle" uniqKey="Marenne G" first="Gaelle" last="Marenne">Gaelle Marenne</name><affiliation wicri:level="3"><nlm:aff id="A32"> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Prokunina Olsson, Ludmila" sort="Prokunina Olsson, Ludmila" uniqKey="Prokunina Olsson L" first="Ludmila" last="Prokunina-Olsson">Ludmila Prokunina-Olsson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Baris, Dalsu" sort="Baris, Dalsu" uniqKey="Baris D" first="Dalsu" last="Baris">Dalsu Baris</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schwenn, Molly" sort="Schwenn, Molly" uniqKey="Schwenn M" first="Molly" last="Schwenn">Molly Schwenn</name><affiliation wicri:level="2"><nlm:aff id="A33"> Maine Cancer Registry, Augusta, Maine, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Maine Cancer Registry, Augusta, Maine</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Johnson, Alison" sort="Johnson, Alison" uniqKey="Johnson A" first="Alison" last="Johnson">Alison Johnson</name><affiliation wicri:level="2"><nlm:aff id="A34"> Vermont Cancer Registry, Burlington, Vermont, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vermont Cancer Registry, Burlington, Vermont</wicri:regionArea><placeName><region type="state">Vermont</region></placeName></affiliation></author><author><name sortKey="Landi, Maria Teresa" sort="Landi, Maria Teresa" uniqKey="Landi M" first="Maria Teresa" last="Landi">Maria Teresa Landi</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Goldin, Lynn" sort="Goldin, Lynn" uniqKey="Goldin L" first="Lynn" last="Goldin">Lynn Goldin</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Consonni, Dario" sort="Consonni, Dario" uniqKey="Consonni D" first="Dario" last="Consonni">Dario Consonni</name><affiliation wicri:level="1"><nlm:aff id="A35"> Department of Occupational and Environmental Health , University of Milan, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Department of Occupational and Environmental Health , University of Milan, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A36"> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation></author><author><name sortKey="Bertazzi, Pier Alberto" sort="Bertazzi, Pier Alberto" uniqKey="Bertazzi P" first="Pier Alberto" last="Bertazzi">Pier Alberto Bertazzi</name><affiliation wicri:level="1"><nlm:aff id="A35"> Department of Occupational and Environmental Health , University of Milan, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Department of Occupational and Environmental Health , University of Milan, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A36"> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation></author><author><name sortKey="Rotunno, Melissa" sort="Rotunno, Melissa" uniqKey="Rotunno M" first="Melissa" last="Rotunno">Melissa Rotunno</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rajaraman, Preetha" sort="Rajaraman, Preetha" uniqKey="Rajaraman P" first="Preetha" last="Rajaraman">Preetha Rajaraman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Andersson, Ulrika" sort="Andersson, Ulrika" uniqKey="Andersson U" first="Ulrika" last="Andersson">Ulrika Andersson</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Freeman, Laura E Beane" sort="Freeman, Laura E Beane" uniqKey="Freeman L" first="Laura E Beane" last="Freeman">Laura E Beane Freeman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berg, Christine D" sort="Berg, Christine D" uniqKey="Berg C" first="Christine D" last="Berg">Christine D. Berg</name><affiliation wicri:level="2"><nlm:aff id="A38"> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><affiliation wicri:level="2"><nlm:aff id="A39"> Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Butler, Mary A" sort="Butler, Mary A" uniqKey="Butler M" first="Mary A" last="Butler">Mary A. Butler</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Carreon, Tania" sort="Carreon, Tania" uniqKey="Carreon T" first="Tania" last="Carreon">Tania Carreon</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Feychting, Maria" sort="Feychting, Maria" uniqKey="Feychting M" first="Maria" last="Feychting">Maria Feychting</name><affiliation wicri:level="3"><nlm:aff id="A42"> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ahlbom, Anders" sort="Ahlbom, Anders" uniqKey="Ahlbom A" first="Anders" last="Ahlbom">Anders Ahlbom</name><affiliation wicri:level="3"><nlm:aff id="A42"> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43"> Division of Aging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Aging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A44"> Massachusetts Veteran’s Epidemiology, Research and Information Center, Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Massachusetts Veteran’s Epidemiology, Research and Information Center, Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation wicri:level="3"><nlm:aff id="A45"> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A46"> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Goran" last="Hallmans">Goran Hallmans</name><affiliation wicri:level="1"><nlm:aff id="A47"> Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Public Health and Clinical Medicine, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E" last="Hankinson">Susan E. Hankinson</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Henriksson, Roger" sort="Henriksson, Roger" uniqKey="Henriksson R" first="Roger" last="Henriksson">Roger Henriksson</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A49"> Department of Oncology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Oncology, Karolinska University Hospital, SE-171 76 Stockholm</wicri:regionArea><wicri:noRegion>SE-171 76 Stockholm</wicri:noRegion></affiliation></author><author><name sortKey="Inskip, Peter D" sort="Inskip, Peter D" uniqKey="Inskip P" first="Peter D" last="Inskip">Peter D. Inskip</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Johansen, Christoffer" sort="Johansen, Christoffer" uniqKey="Johansen C" first="Christoffer" last="Johansen">Christoffer Johansen</name><affiliation wicri:level="3"><nlm:aff id="A50"> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Landgren, Annelie" sort="Landgren, Annelie" uniqKey="Landgren A" first="Annelie" last="Landgren">Annelie Landgren</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mckean Cowdin, Roberta" sort="Mckean Cowdin, Roberta" uniqKey="Mckean Cowdin R" first="Roberta" last="Mckean-Cowdin">Roberta Mckean-Cowdin</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Michaud, Dominique S" sort="Michaud, Dominique S" uniqKey="Michaud D" first="Dominique S" last="Michaud">Dominique S. Michaud</name><affiliation wicri:level="3"><nlm:aff id="A51"> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A52"> Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Melin, Beatrice S" sort="Melin, Beatrice S" uniqKey="Melin B" first="Beatrice S" last="Melin">Beatrice S. Melin</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A54"> Department of Epidemiology, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Ruder, Avima M" sort="Ruder, Avima M" uniqKey="Ruder A" first="Avima M" last="Ruder">Avima M. Ruder</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="3"><nlm:aff id="A45"> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A46"> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Visvanathan, Kala" sort="Visvanathan, Kala" uniqKey="Visvanathan K" first="Kala" last="Visvanathan">Kala Visvanathan</name><affiliation wicri:level="2"><nlm:aff id="A55"> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A54"> Department of Epidemiology, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation wicri:level="3"><nlm:aff id="A56"> Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation wicri:level="2"><nlm:aff id="A57"> Division of Epidemiology, Department of Environmental Medicine, NYU School of Medicine, New York, NY</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea> Division of Epidemiology, Department of Environmental Medicine, NYU School of Medicine, New York</wicri:cityArea></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Silverman, Debra T" sort="Silverman, Debra T" uniqKey="Silverman D" first="Debra T" last="Silverman">Debra T. Silverman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><affiliation wicri:level="3"><nlm:aff id="A58"> National School of Public Health, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea> National School of Public Health, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61"> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP), Barcelona</nlm:aff><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName><wicri:orgArea> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP)</wicri:orgArea></affiliation></author><author><name sortKey="Gonzalez, Juan R" sort="Gonzalez, Juan R" uniqKey="Gonzalez J" first="Juan R" last="Gonzalez">Juan R. Gonzalez</name><affiliation wicri:level="3"><nlm:aff id="A59"> Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Centre for Research in Environmental Epidemiology (CREAL), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61"> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP), Barcelona</nlm:aff><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName><wicri:orgArea> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP)</wicri:orgArea></affiliation></author><author><name sortKey="Villa, Olaya" sort="Villa, Olaya" uniqKey="Villa O" first="Olaya" last="Villa">Olaya Villa</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A5"> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona</wicri:regionArea><wicri:noRegion>E-08003 Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Li, Donghui" sort="Li, Donghui" uniqKey="Li D" first="Donghui" last="Li">Donghui Li</name><affiliation wicri:level="2"><nlm:aff id="A62"> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name><affiliation wicri:level="3"><nlm:aff id="A63"> Catalan Institute of Oncology (ICO), Institut d’Investigació Biomèdica de Bellvitge (IDIBELL ), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Catalan Institute of Oncology (ICO), Institut d’Investigació Biomèdica de Bellvitge (IDIBELL ), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A" last="Risch">Harvey A. Risch</name><affiliation wicri:level="2"><nlm:aff id="A64"> Yale University School of Public Health, New Haven, CT, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Yale University School of Public Health, New Haven, CT</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H" last="Olson">Sara H. Olson</name><affiliation wicri:level="2"><nlm:aff id="A65"> Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wolpin, Brian M" sort="Wolpin, Brian M" uniqKey="Wolpin B" first="Brian M" last="Wolpin">Brian M. Wolpin</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66"> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Jiao, Li" sort="Jiao, Li" uniqKey="Jiao L" first="Li" last="Jiao">Li Jiao</name><affiliation wicri:level="2"><nlm:aff id="A67"> Department of Medicine, Baylor College of Medicine, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, Baylor College of Medicine, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hassan, Manal" sort="Hassan, Manal" uniqKey="Hassan M" first="Manal" last="Hassan">Manal Hassan</name><affiliation wicri:level="2"><nlm:aff id="A62"> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Wheeler, William" sort="Wheeler, William" uniqKey="Wheeler W" first="William" last="Wheeler">William Wheeler</name><affiliation wicri:level="2"><nlm:aff id="A68"> Information Management Services, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Information Management Services, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Arslan, Alan A" sort="Arslan, Alan A" uniqKey="Arslan A" first="Alan A" last="Arslan">Alan A. Arslan</name><affiliation wicri:level="2"><nlm:aff id="A69"> Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A71"> New York University Cancer Institute, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> New York University Cancer Institute, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Bas Bueno De Mesquita, H" sort="Bas Bueno De Mesquita, H" uniqKey="Bas Bueno De Mesquita H" first="H" last="Bas Bueno-De-Mesquita">H. Bas Bueno-De-Mesquita</name><affiliation wicri:level="3"><nlm:aff id="A72"> Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea> Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A73"> National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea> National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S" last="Fuchs">Charles S. Fuchs</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66"> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Gallinger, Steven" sort="Gallinger, Steven" uniqKey="Gallinger S" first="Steven" last="Gallinger">Steven Gallinger</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Gross, Myron D" sort="Gross, Myron D" uniqKey="Gross M" first="Myron D" last="Gross">Myron D. Gross</name><affiliation wicri:level="2"><nlm:aff id="A75"> Department of Laboratory Medicine and Pathology, School of Medicine, University of Minnesota, Minneapolis, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Laboratory Medicine and Pathology, School of Medicine, University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A" last="Holly">Elizabeth A. Holly</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Klein, Alison P" sort="Klein, Alison P" uniqKey="Klein A" first="Alison P" last="Klein">Alison P. Klein</name><affiliation wicri:level="2"><nlm:aff id="A77"> Department of Oncology, the Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, the Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Lacroix, Andrea" sort="Lacroix, Andrea" uniqKey="Lacroix A" first="Andrea" last="Lacroix">Andrea Lacroix</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mandelson, Margaret T" sort="Mandelson, Margaret T" uniqKey="Mandelson M" first="Margaret T" last="Mandelson">Margaret T. Mandelson</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A78"> Group Health Center for Health Studies, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Group Health Center for Health Studies, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Petersen, Gloria" sort="Petersen, Gloria" uniqKey="Petersen G" first="Gloria" last="Petersen">Gloria Petersen</name><affiliation wicri:level="2"><nlm:aff id="A79"> Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name><affiliation wicri:level="1"><nlm:aff id="A80"> Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Sud University, Institut Gustave-Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea> Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Sud University, Institut Gustave-Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name><affiliation wicri:level="3"><nlm:aff id="A81"> Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea> Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chang, Kenneth" sort="Chang, Kenneth" uniqKey="Chang K" first="Kenneth" last="Chang">Kenneth Chang</name><affiliation wicri:level="2"><nlm:aff id="A82"> Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cotterchio, Michelle" sort="Cotterchio, Michelle" uniqKey="Cotterchio M" first="Michelle" last="Cotterchio">Michelle Cotterchio</name><affiliation wicri:level="4"><nlm:aff id="A83"> Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A85"> Department of Nutrition, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Nutrition, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Goggins, Michael" sort="Goggins, Michael" uniqKey="Goggins M" first="Michael" last="Goggins">Michael Goggins</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A86"> Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87"> Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bolton, Judith A Hoffman" sort="Bolton, Judith A Hoffman" uniqKey="Bolton J" first="Judith A Hoffman" last="Bolton">Judith A Hoffman Bolton</name><affiliation wicri:level="2"><nlm:aff id="A55"> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jenab, Mazda" sort="Jenab, Mazda" uniqKey="Jenab M" first="Mazda" last="Jenab">Mazda Jenab</name><affiliation wicri:level="3"><nlm:aff id="A88"> International Agency for Research on Cancer (IARC/WHO), Lyon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea> International Agency for Research on Cancer (IARC/WHO), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A89"> Department of Public Health and Primary Care, Clinical Gerontology, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Department of Public Health and Primary Care, Clinical Gerontology, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Krogh, Vittorio" sort="Krogh, Vittorio" uniqKey="Krogh V" first="Vittorio" last="Krogh">Vittorio Krogh</name><affiliation wicri:level="3"><nlm:aff id="A90"> Nutritional Epidemiology Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Nazionale dei Tumori, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Nutritional Epidemiology Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Nazionale dei Tumori, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Kurtz, Robert C" sort="Kurtz, Robert C" uniqKey="Kurtz R" first="Robert C" last="Kurtz">Robert C. Kurtz</name><affiliation wicri:level="2"><nlm:aff id="A91"> Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Mcwilliams, Robert R" sort="Mcwilliams, Robert R" uniqKey="Mcwilliams R" first="Robert R" last="Mcwilliams">Robert R. Mcwilliams</name><affiliation wicri:level="2"><nlm:aff id="A92"> Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Medical Oncology, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Mendelsohn, Julie B" sort="Mendelsohn, Julie B" uniqKey="Mendelsohn J" first="Julie B" last="Mendelsohn">Julie B. Mendelsohn</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rabe, Kari G" sort="Rabe, Kari G" uniqKey="Rabe K" first="Kari G" last="Rabe">Kari G. Rabe</name><affiliation wicri:level="2"><nlm:aff id="A79"> Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="3"><nlm:aff id="A51"> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation wicri:level="3"><nlm:aff id="A50"> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Tobias, Geoffrey S" sort="Tobias, Geoffrey S" uniqKey="Tobias G" first="Geoffrey S" last="Tobias">Geoffrey S. Tobias</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A93"> Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea> Bureau of Epidemiologic Research, Academy of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Elena, Joanne W" sort="Elena, Joanne W" uniqKey="Elena J" first="Joanne W" last="Elena">Joanne W. Elena</name><affiliation wicri:level="2"><nlm:aff id="A38"> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yu, Herbert" sort="Yu, Herbert" uniqKey="Yu H" first="Herbert" last="Yu">Herbert Yu</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Amundadottir, Laufey" sort="Amundadottir, Laufey" uniqKey="Amundadottir L" first="Laufey" last="Amundadottir">Laufey Amundadottir</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Stolzenberg Solomon, Rachael Z" sort="Stolzenberg Solomon, Rachael Z" uniqKey="Stolzenberg Solomon R" first="Rachael Z" last="Stolzenberg-Solomon">Rachael Z. Stolzenberg-Solomon</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Schumacher, Fredrick" sort="Schumacher, Fredrick" uniqKey="Schumacher F" first="Fredrick" last="Schumacher">Fredrick Schumacher</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Stram, Daniel" sort="Stram, Daniel" uniqKey="Stram D" first="Daniel" last="Stram">Daniel Stram</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Savage, Sharon A" sort="Savage, Sharon A" uniqKey="Savage S" first="Sharon A" last="Savage">Sharon A. Savage</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mirabello, Lisa" sort="Mirabello, Lisa" uniqKey="Mirabello L" first="Lisa" last="Mirabello">Lisa Mirabello</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A94"> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wunder, Jay S" sort="Wunder, Jay S" uniqKey="Wunder J" first="Jay S" last="Wunder">Jay S. Wunder</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A94"> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Ana Pati O" sort="Garcia, Ana Pati O" uniqKey="Garcia A" first="Ana Pati O" last="García">Ana Pati O García</name><affiliation wicri:level="1"><nlm:aff id="A95"> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona</wicri:regionArea><wicri:noRegion>E31080 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Sierrasesumaga, Luis" sort="Sierrasesumaga, Luis" uniqKey="Sierrasesumaga L" first="Luis" last="Sierrasesúmaga">Luis Sierrasesúmaga</name><affiliation wicri:level="1"><nlm:aff id="A95"> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona</wicri:regionArea><wicri:noRegion>E31080 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Barkauskas, Donald A" sort="Barkauskas, Donald A" uniqKey="Barkauskas D" first="Donald A" last="Barkauskas">Donald A. Barkauskas</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Gorlick, Richard G" sort="Gorlick, Richard G" uniqKey="Gorlick R" first="Richard G" last="Gorlick">Richard G. Gorlick</name><affiliation wicri:level="2"><nlm:aff id="A96"> Department of Molecular Pharmacology , Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Molecular Pharmacology , Albert Einstein College of Medicine of Yeshiva University, Bronx, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A97"> Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chow, Wong Ho" sort="Chow, Wong Ho" uniqKey="Chow W" first="Wong-Ho" last="Chow">Wong-Ho Chow</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Moore, Lee E" sort="Moore, Lee E" uniqKey="Moore L" first="Lee E" last="Moore">Lee E. Moore</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schwartz, Kendra L" sort="Schwartz, Kendra L" uniqKey="Schwartz K" first="Kendra L" last="Schwartz">Kendra L. Schwartz</name><affiliation wicri:level="2"><nlm:aff id="A98"> Department of Family Medicine and Public Health Sciences, Wayne State University, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Family Medicine and Public Health Sciences, Wayne State University, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Davis, Faith G" sort="Davis, Faith G" uniqKey="Davis F" first="Faith G" last="Davis">Faith G. Davis</name><affiliation wicri:level="4"><nlm:aff id="A99"> Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region><settlement type="city">Chicago</settlement></placeName><orgName type="university">Université de l'Illinois à Chicago</orgName></affiliation></author><author><name sortKey="Hsing, Ann W" sort="Hsing, Ann W" uniqKey="Hsing A" first="Ann W" last="Hsing">Ann W. Hsing</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Black, Amanda" sort="Black, Amanda" uniqKey="Black A" first="Amanda" last="Black">Amanda Black</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Wentzensen, Nicolas" sort="Wentzensen, Nicolas" uniqKey="Wentzensen N" first="Nicolas" last="Wentzensen">Nicolas Wentzensen</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A" last="Brinton">Louise A. Brinton</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><nlm:aff id="A100"> Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea> Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Peplonska, Beata" sort="Peplonska, Beata" uniqKey="Peplonska B" first="Beata" last="Peplonska">Beata Peplonska</name><affiliation wicri:level="1"><nlm:aff id="A101"> Nofer Institute of Occupational Medicine, Lodz, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea> Nofer Institute of Occupational Medicine, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Mcglynn, Katherine A" sort="Mcglynn, Katherine A" uniqKey="Mcglynn K" first="Katherine A" last="Mcglynn">Katherine A. Mcglynn</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Cook, Michael B" sort="Cook, Michael B" uniqKey="Cook M" first="Michael B" last="Cook">Michael B. Cook</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Graubard, Barry I" sort="Graubard, Barry I" uniqKey="Graubard B" first="Barry I" last="Graubard">Barry I. Graubard</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kratz, Christian P" sort="Kratz, Christian P" uniqKey="Kratz C" first="Christian P" last="Kratz">Christian P. Kratz</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A102"> Zentrum für Kinderheilkunde und Jugendmedizin, Klinik für Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea> Zentrum für Kinderheilkunde und Jugendmedizin, Klinik für Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Erickson, Ralph L" sort="Erickson, Ralph L" uniqKey="Erickson R" first="Ralph L" last="Erickson">Ralph L. Erickson</name><affiliation wicri:level="2"><nlm:aff id="A103"> Walter Reed Army Institute of Research, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Walter Reed Army Institute of Research, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Thomas, Gilles" sort="Thomas, Gilles" uniqKey="Thomas G" first="Gilles" last="Thomas">Gilles Thomas</name><affiliation wicri:level="2"><nlm:aff id="A103"> Walter Reed Army Institute of Research, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Walter Reed Army Institute of Research, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hoover, Robert N" sort="Hoover, Robert N" uniqKey="Hoover R" first="Robert N" last="Hoover">Robert N. Hoover</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Real, Francisco X" sort="Real, Francisco X" uniqKey="Real F" first="Francisco X" last="Real">Francisco X. Real</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A105"> Epithelial Carcinogenesis Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Epithelial Carcinogenesis Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F" last="Fraumeni">Joseph F. Fraumeni</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Caporaso, Neil E" sort="Caporaso, Neil E" uniqKey="Caporaso N" first="Neil E" last="Caporaso">Neil E. Caporaso</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Tucker, Margaret" sort="Tucker, Margaret" uniqKey="Tucker M" first="Margaret" last="Tucker">Margaret Tucker</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Perez Jurado, Luis A" sort="Perez Jurado, Luis A" uniqKey="Perez Jurado L" first="Luis A" last="Pérez-Jurado">Luis A. Pérez-Jurado</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A4"> Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), E-08003 Barcelona</wicri:regionArea><wicri:noRegion>E-08003 Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22561519</idno><idno type="pmc">3372921</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372921</idno><idno type="RBID">PMC:3372921</idno><idno type="doi">10.1038/ng.2270</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002E14</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E14</idno><idno type="wicri:Area/Pmc/Curation">002C64</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C64</idno><idno type="wicri:Area/Pmc/Checkpoint">001F83</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001F83</idno><idno type="wicri:Area/Ncbi/Merge">000E05</idno><idno type="wicri:Area/Ncbi/Curation">000E05</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E05</idno><idno type="wicri:doubleKey">1061-4036:2012:Jacobs K:detectable:clonal:mosaicism</idno><idno type="wicri:Area/Main/Merge">005660</idno><idno type="wicri:Area/Main/Curation">005412</idno><idno type="wicri:Area/Main/Exploration">005412</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Detectable clonal mosaicism and its relationship to aging and cancer</title><author><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B" last="Jacobs">Kevin B. Jacobs</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Zhou, Weiyin" sort="Zhou, Weiyin" uniqKey="Zhou W" first="Weiyin" last="Zhou">Weiyin Zhou</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Wacholder, Sholom" sort="Wacholder, Sholom" uniqKey="Wacholder S" first="Sholom" last="Wacholder">Sholom Wacholder</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rodriguez Santiago, Benjamin" sort="Rodriguez Santiago, Benjamin" uniqKey="Rodriguez Santiago B" first="Benjamin" last="Rodriguez-Santiago">Benjamin Rodriguez-Santiago</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A5"> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona</wicri:regionArea><wicri:noRegion>E-08003 Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Deng, Xiang" sort="Deng, Xiang" uniqKey="Deng X" first="Xiang" last="Deng">Xiang Deng</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Liu, Chenwei" sort="Liu, Chenwei" uniqKey="Liu C" first="Chenwei" last="Liu">Chenwei Liu</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Horner, Marie Josephe" sort="Horner, Marie Josephe" uniqKey="Horner M" first="Marie-Josephe" last="Horner">Marie-Josephe Horner</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Cullen, Michael" sort="Cullen, Michael" uniqKey="Cullen M" first="Michael" last="Cullen">Michael Cullen</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Epstein, Caroline G" sort="Epstein, Caroline G" uniqKey="Epstein C" first="Caroline G" last="Epstein">Caroline G. Epstein</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Dean, Michael C" sort="Dean, Michael C" uniqKey="Dean M" first="Michael C" last="Dean">Michael C. Dean</name><affiliation wicri:level="2"><nlm:aff id="A6"> Laboratory of Experimental Immunology, Center for Cancer Research, NCI- Frederick, Frederick, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Laboratory of Experimental Immunology, Center for Cancer Research, NCI- Frederick, Frederick, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chatterjee, Nilanjan" sort="Chatterjee, Nilanjan" uniqKey="Chatterjee N" first="Nilanjan" last="Chatterjee">Nilanjan Chatterjee</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Sampson, Joshua" sort="Sampson, Joshua" uniqKey="Sampson J" first="Joshua" last="Sampson">Joshua Sampson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C" last="Chung">Charles C. Chung</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kovaks, Joseph" sort="Kovaks, Joseph" uniqKey="Kovaks J" first="Joseph" last="Kovaks">Joseph Kovaks</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Teras, Lauren T" sort="Teras, Lauren T" uniqKey="Teras L" first="Lauren T" last="Teras">Lauren T. Teras</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M" last="Gaudet">Mia M. Gaudet</name><affiliation wicri:level="2"><nlm:aff id="A7"> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Research Program, American Cancer Society, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Weinstein, Stephanie J" sort="Weinstein, Stephanie J" uniqKey="Weinstein S" first="Stephanie J" last="Weinstein">Stephanie J. Weinstein</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name><affiliation wicri:level="1"><nlm:aff id="A8"> Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea> Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Abnet, Christian C" sort="Abnet, Christian C" uniqKey="Abnet C" first="Christian C" last="Abnet">Christian C. Abnet</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Goldstein, Alisa M" sort="Goldstein, Alisa M" uniqKey="Goldstein A" first="Alisa M" last="Goldstein">Alisa M. Goldstein</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hu, Nan" sort="Hu, Nan" uniqKey="Hu N" first="Nan" last="Hu">Nan Hu</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yu, Kai" sort="Yu, Kai" uniqKey="Yu K" first="Kai" last="Yu">Kai Yu</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yuan, Jian Min" sort="Yuan, Jian Min" uniqKey="Yuan J" first="Jian-Min" last="Yuan">Jian-Min Yuan</name><affiliation wicri:level="2"><nlm:aff id="A9"> Department of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10"> University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Liao, Linda" sort="Liao, Linda" uniqKey="Liao L" first="Linda" last="Liao">Linda Liao</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ding, Ti" sort="Ding, Ti" uniqKey="Ding T" first="Ti" last="Ding">Ti Ding</name><affiliation wicri:level="1"><nlm:aff id="A11"> Shanxi Cancer Hospital, Taiyuan, Shanxi, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanxi Cancer Hospital, Taiyuan, Shanxi</wicri:regionArea><wicri:noRegion>Shanxi</wicri:noRegion></affiliation></author><author><name sortKey="Qiao, You Lin" sort="Qiao, You Lin" uniqKey="Qiao Y" first="You-Lin" last="Qiao">You-Lin Qiao</name><affiliation wicri:level="3"><nlm:aff id="A12"> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation wicri:level="1"><nlm:aff id="A13"> Shanghai Cancer Institute, Shanghai, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanghai Cancer Institute, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Koh, Woon Puay" sort="Koh, Woon Puay" uniqKey="Koh W" first="Woon-Puay" last="Koh">Woon-Puay Koh</name><affiliation wicri:level="4"><nlm:aff id="A14"> Saw Swee Hock School of Public Health, National University of Singapore, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea> Saw Swee Hock School of Public Health, National University of Singapore</wicri:regionArea><orgName type="university">Université nationale de Singapour</orgName></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation wicri:level="1"><nlm:aff id="A13"> Shanghai Cancer Institute, Shanghai, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanghai Cancer Institute, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Tang, Ze Zhong" sort="Tang, Ze Zhong" uniqKey="Tang Z" first="Ze-Zhong" last="Tang">Ze-Zhong Tang</name><affiliation wicri:level="1"><nlm:aff id="A11"> Shanxi Cancer Hospital, Taiyuan, Shanxi, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Shanxi Cancer Hospital, Taiyuan, Shanxi</wicri:regionArea><wicri:noRegion>Shanxi</wicri:noRegion></affiliation></author><author><name sortKey="Fan, Jin Hu" sort="Fan, Jin Hu" uniqKey="Fan J" first="Jin-Hu" last="Fan">Jin-Hu Fan</name><affiliation wicri:level="3"><nlm:aff id="A12"> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing, People’s Republic of China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea> Department of Epidemiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><affiliation wicri:level="2"><nlm:aff id="A15"> Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Thoracic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Amos, Christopher" sort="Amos, Christopher" uniqKey="Amos C" first="Christopher" last="Amos">Christopher Amos</name><affiliation wicri:level="2"><nlm:aff id="A17"> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Blot, William J" sort="Blot, William J" uniqKey="Blot W" first="William J" last="Blot">William J. Blot</name><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A18"> International Epidemiology Institute, Rockville, Maryland 20850, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> International Epidemiology Institute, Rockville, Maryland 20850</wicri:regionArea><wicri:noRegion>Maryland 20850</wicri:noRegion></affiliation></author><author><name sortKey="Bock, Cathryn H" sort="Bock, Cathryn H" uniqKey="Bock C" first="Cathryn H" last="Bock">Cathryn H. Bock</name><affiliation wicri:level="2"><nlm:aff id="A19"> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20"> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Gillanders, Elizabeth M" sort="Gillanders, Elizabeth M" uniqKey="Gillanders E" first="Elizabeth M" last="Gillanders">Elizabeth M. Gillanders</name><affiliation wicri:level="1"><nlm:aff id="A21"> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Harris, Curtis C" sort="Harris, Curtis C" uniqKey="Harris C" first="Curtis C" last="Harris">Curtis C. Harris</name><affiliation wicri:level="1"><nlm:aff id="A22"> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N" last="Kolonel">Laurence N. Kolonel</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Mcneill, Lorna H" sort="Mcneill, Lorna H" uniqKey="Mcneill L" first="Lorna H" last="Mcneill">Lorna H. Mcneill</name><affiliation wicri:level="1"><nlm:aff id="A25"> Department of Health Disparities Research, Division of Office of the Vice-President, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas , USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Disparities Research, Division of Office of the Vice-President, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas </wicri:regionArea><wicri:noRegion>Texas </wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A26"> Center for Community Engaged Translational Research , Duncan Family Institute, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Center for Community Engaged Translational Research , Duncan Family Institute, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Rybicki, Benjamin A" sort="Rybicki, Benjamin A" uniqKey="Rybicki B" first="Benjamin A" last="Rybicki">Benjamin A. Rybicki</name><affiliation wicri:level="1"><nlm:aff id="A27"> Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan 48202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan 48202</wicri:regionArea><wicri:noRegion>Michigan 48202</wicri:noRegion></affiliation></author><author><name sortKey="Schwartz, Ann G" sort="Schwartz, Ann G" uniqKey="Schwartz A" first="Ann G" last="Schwartz">Ann G. Schwartz</name><affiliation wicri:level="2"><nlm:aff id="A19"> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Karmanos Cancer Institute, Wayne State University, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20"> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Signorello, Lisa B" sort="Signorello, Lisa B" uniqKey="Signorello L" first="Lisa B" last="Signorello">Lisa B. Signorello</name><affiliation wicri:level="2"><nlm:aff id="A16"> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology in the Department of Medicine, Vanderbilt Epidemiology Center,Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A18"> International Epidemiology Institute, Rockville, Maryland 20850, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> International Epidemiology Institute, Rockville, Maryland 20850</wicri:regionArea><wicri:noRegion>Maryland 20850</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Spitz, Margaret R" sort="Spitz, Margaret R" uniqKey="Spitz M" first="Margaret R" last="Spitz">Margaret R. Spitz</name><affiliation wicri:level="2"><nlm:aff id="A29"> Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Wiencke, John K" sort="Wiencke, John K" uniqKey="Wiencke J" first="John K" last="Wiencke">John K. Wiencke</name><affiliation wicri:level="1"><nlm:aff id="A30"> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158</wicri:regionArea><wicri:noRegion>California 94158</wicri:noRegion></affiliation></author><author><name sortKey="Wrensch, Margaret" sort="Wrensch, Margaret" uniqKey="Wrensch M" first="Margaret" last="Wrensch">Margaret Wrensch</name><affiliation wicri:level="1"><nlm:aff id="A30"> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Neurological Surgery, University of California San Francisco , San Francisco, California 94158</wicri:regionArea><wicri:noRegion>California 94158</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><affiliation wicri:level="2"><nlm:aff id="A17"> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Zanetti, Krista A" sort="Zanetti, Krista A" uniqKey="Zanetti K" first="Krista A" last="Zanetti">Krista A. Zanetti</name><affiliation wicri:level="1"><nlm:aff id="A21"> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A22"> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892</wicri:regionArea><wicri:noRegion>Maryland 20892</wicri:noRegion></affiliation></author><author><name sortKey="Ziegler, Regina G" sort="Ziegler, Regina G" uniqKey="Ziegler R" first="Regina G" last="Ziegler">Regina G. Ziegler</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D" last="Figueroa">Jonine D. Figueroa</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A31"> Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Genetics and Epidemiology, Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Malats, Nuria" sort="Malats, Nuria" uniqKey="Malats N" first="Nuria" last="Malats">Nuria Malats</name><affiliation wicri:level="3"><nlm:aff id="A32"> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Marenne, Gaelle" sort="Marenne, Gaelle" uniqKey="Marenne G" first="Gaelle" last="Marenne">Gaelle Marenne</name><affiliation wicri:level="3"><nlm:aff id="A32"> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Genetics and Molecular Epidemiology Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Prokunina Olsson, Ludmila" sort="Prokunina Olsson, Ludmila" uniqKey="Prokunina Olsson L" first="Ludmila" last="Prokunina-Olsson">Ludmila Prokunina-Olsson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Baris, Dalsu" sort="Baris, Dalsu" uniqKey="Baris D" first="Dalsu" last="Baris">Dalsu Baris</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schwenn, Molly" sort="Schwenn, Molly" uniqKey="Schwenn M" first="Molly" last="Schwenn">Molly Schwenn</name><affiliation wicri:level="2"><nlm:aff id="A33"> Maine Cancer Registry, Augusta, Maine, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Maine Cancer Registry, Augusta, Maine</wicri:regionArea><placeName><region type="state">Maine (État)</region></placeName></affiliation></author><author><name sortKey="Johnson, Alison" sort="Johnson, Alison" uniqKey="Johnson A" first="Alison" last="Johnson">Alison Johnson</name><affiliation wicri:level="2"><nlm:aff id="A34"> Vermont Cancer Registry, Burlington, Vermont, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vermont Cancer Registry, Burlington, Vermont</wicri:regionArea><placeName><region type="state">Vermont</region></placeName></affiliation></author><author><name sortKey="Landi, Maria Teresa" sort="Landi, Maria Teresa" uniqKey="Landi M" first="Maria Teresa" last="Landi">Maria Teresa Landi</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Goldin, Lynn" sort="Goldin, Lynn" uniqKey="Goldin L" first="Lynn" last="Goldin">Lynn Goldin</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Consonni, Dario" sort="Consonni, Dario" uniqKey="Consonni D" first="Dario" last="Consonni">Dario Consonni</name><affiliation wicri:level="1"><nlm:aff id="A35"> Department of Occupational and Environmental Health , University of Milan, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Department of Occupational and Environmental Health , University of Milan, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A36"> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation></author><author><name sortKey="Bertazzi, Pier Alberto" sort="Bertazzi, Pier Alberto" uniqKey="Bertazzi P" first="Pier Alberto" last="Bertazzi">Pier Alberto Bertazzi</name><affiliation wicri:level="1"><nlm:aff id="A35"> Department of Occupational and Environmental Health , University of Milan, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Department of Occupational and Environmental Health , University of Milan, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A36"> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Unit of Epidemiology, Fondazione Istituto di Ricevero e Cura a Carattere Scientifico (IRCCS), Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, 20122</wicri:regionArea><wicri:noRegion>20122</wicri:noRegion></affiliation></author><author><name sortKey="Rotunno, Melissa" sort="Rotunno, Melissa" uniqKey="Rotunno M" first="Melissa" last="Rotunno">Melissa Rotunno</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rajaraman, Preetha" sort="Rajaraman, Preetha" uniqKey="Rajaraman P" first="Preetha" last="Rajaraman">Preetha Rajaraman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Andersson, Ulrika" sort="Andersson, Ulrika" uniqKey="Andersson U" first="Ulrika" last="Andersson">Ulrika Andersson</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Freeman, Laura E Beane" sort="Freeman, Laura E Beane" uniqKey="Freeman L" first="Laura E Beane" last="Freeman">Laura E Beane Freeman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berg, Christine D" sort="Berg, Christine D" uniqKey="Berg C" first="Christine D" last="Berg">Christine D. Berg</name><affiliation wicri:level="2"><nlm:aff id="A38"> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><affiliation wicri:level="2"><nlm:aff id="A39"> Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Butler, Mary A" sort="Butler, Mary A" uniqKey="Butler M" first="Mary A" last="Butler">Mary A. Butler</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Carreon, Tania" sort="Carreon, Tania" uniqKey="Carreon T" first="Tania" last="Carreon">Tania Carreon</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Feychting, Maria" sort="Feychting, Maria" uniqKey="Feychting M" first="Maria" last="Feychting">Maria Feychting</name><affiliation wicri:level="3"><nlm:aff id="A42"> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ahlbom, Anders" sort="Ahlbom, Anders" uniqKey="Ahlbom A" first="Anders" last="Ahlbom">Anders Ahlbom</name><affiliation wicri:level="3"><nlm:aff id="A42"> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A43"> Division of Aging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Aging, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A44"> Massachusetts Veteran’s Epidemiology, Research and Information Center, Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Massachusetts Veteran’s Epidemiology, Research and Information Center, Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name><affiliation wicri:level="3"><nlm:aff id="A45"> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A46"> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Hallmans, Goran" sort="Hallmans, Goran" uniqKey="Hallmans G" first="Goran" last="Hallmans">Goran Hallmans</name><affiliation wicri:level="1"><nlm:aff id="A47"> Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Public Health and Clinical Medicine, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E" last="Hankinson">Susan E. Hankinson</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Henriksson, Roger" sort="Henriksson, Roger" uniqKey="Henriksson R" first="Roger" last="Henriksson">Roger Henriksson</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A49"> Department of Oncology, Karolinska University Hospital, SE-171 76 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Oncology, Karolinska University Hospital, SE-171 76 Stockholm</wicri:regionArea><wicri:noRegion>SE-171 76 Stockholm</wicri:noRegion></affiliation></author><author><name sortKey="Inskip, Peter D" sort="Inskip, Peter D" uniqKey="Inskip P" first="Peter D" last="Inskip">Peter D. Inskip</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Johansen, Christoffer" sort="Johansen, Christoffer" uniqKey="Johansen C" first="Christoffer" last="Johansen">Christoffer Johansen</name><affiliation wicri:level="3"><nlm:aff id="A50"> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Landgren, Annelie" sort="Landgren, Annelie" uniqKey="Landgren A" first="Annelie" last="Landgren">Annelie Landgren</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mckean Cowdin, Roberta" sort="Mckean Cowdin, Roberta" uniqKey="Mckean Cowdin R" first="Roberta" last="Mckean-Cowdin">Roberta Mckean-Cowdin</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Michaud, Dominique S" sort="Michaud, Dominique S" uniqKey="Michaud D" first="Dominique S" last="Michaud">Dominique S. Michaud</name><affiliation wicri:level="3"><nlm:aff id="A51"> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A52"> Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Division of Biology and Medicine, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Melin, Beatrice S" sort="Melin, Beatrice S" uniqKey="Melin B" first="Beatrice S" last="Melin">Beatrice S. Melin</name><affiliation wicri:level="1"><nlm:aff id="A37"> Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Radiation Sciences, Oncology, Umeå University, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A54"> Department of Epidemiology, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Ruder, Avima M" sort="Ruder, Avima M" uniqKey="Ruder A" first="Avima M" last="Ruder">Avima M. Ruder</name><affiliation wicri:level="2"><nlm:aff id="A41"> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name><affiliation wicri:level="2"><nlm:aff id="A40"> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="3"><nlm:aff id="A45"> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Cancer Epidemiology Centre, The Cancer Council of Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A46"> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea> Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Visvanathan, Kala" sort="Visvanathan, Kala" uniqKey="Visvanathan K" first="Kala" last="Visvanathan">Kala Visvanathan</name><affiliation wicri:level="2"><nlm:aff id="A55"> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A54"> Department of Epidemiology, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation wicri:level="3"><nlm:aff id="A56"> Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea> Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation wicri:level="2"><nlm:aff id="A57"> Division of Epidemiology, Department of Environmental Medicine, NYU School of Medicine, New York, NY</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea> Division of Epidemiology, Department of Environmental Medicine, NYU School of Medicine, New York</wicri:cityArea></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation wicri:level="1"><nlm:aff id="A28"> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203,USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203</wicri:regionArea><wicri:noRegion>Tennessee 37203</wicri:noRegion></affiliation></author><author><name sortKey="Silverman, Debra T" sort="Silverman, Debra T" uniqKey="Silverman D" first="Debra T" last="Silverman">Debra T. Silverman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><affiliation wicri:level="3"><nlm:aff id="A58"> National School of Public Health, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea> National School of Public Health, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61"> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP), Barcelona</nlm:aff><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName><wicri:orgArea> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP)</wicri:orgArea></affiliation></author><author><name sortKey="Gonzalez, Juan R" sort="Gonzalez, Juan R" uniqKey="Gonzalez J" first="Juan R" last="Gonzalez">Juan R. Gonzalez</name><affiliation wicri:level="3"><nlm:aff id="A59"> Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Centre for Research in Environmental Epidemiology (CREAL), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61"> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP), Barcelona</nlm:aff><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName><wicri:orgArea> Centro de Investigacion Biomedica en Red Epidemiologia y Slaud Publica (CIBERESP)</wicri:orgArea></affiliation></author><author><name sortKey="Villa, Olaya" sort="Villa, Olaya" uniqKey="Villa O" first="Olaya" last="Villa">Olaya Villa</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A5"> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Quantitative Genomic Medicine Laboratory, qGenomics, E-08003 Barcelona</wicri:regionArea><wicri:noRegion>E-08003 Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Li, Donghui" sort="Li, Donghui" uniqKey="Li D" first="Donghui" last="Li">Donghui Li</name><affiliation wicri:level="2"><nlm:aff id="A62"> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name><affiliation wicri:level="3"><nlm:aff id="A63"> Catalan Institute of Oncology (ICO), Institut d’Investigació Biomèdica de Bellvitge (IDIBELL ), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Catalan Institute of Oncology (ICO), Institut d’Investigació Biomèdica de Bellvitge (IDIBELL ), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A" last="Risch">Harvey A. Risch</name><affiliation wicri:level="2"><nlm:aff id="A64"> Yale University School of Public Health, New Haven, CT, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Yale University School of Public Health, New Haven, CT</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H" last="Olson">Sara H. Olson</name><affiliation wicri:level="2"><nlm:aff id="A65"> Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wolpin, Brian M" sort="Wolpin, Brian M" uniqKey="Wolpin B" first="Brian M" last="Wolpin">Brian M. Wolpin</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66"> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Jiao, Li" sort="Jiao, Li" uniqKey="Jiao L" first="Li" last="Jiao">Li Jiao</name><affiliation wicri:level="2"><nlm:aff id="A67"> Department of Medicine, Baylor College of Medicine, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, Baylor College of Medicine, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Hassan, Manal" sort="Hassan, Manal" uniqKey="Hassan M" first="Manal" last="Hassan">Manal Hassan</name><affiliation wicri:level="2"><nlm:aff id="A62"> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Wheeler, William" sort="Wheeler, William" uniqKey="Wheeler W" first="William" last="Wheeler">William Wheeler</name><affiliation wicri:level="2"><nlm:aff id="A68"> Information Management Services, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Information Management Services, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Arslan, Alan A" sort="Arslan, Alan A" uniqKey="Arslan A" first="Alan A" last="Arslan">Alan A. Arslan</name><affiliation wicri:level="2"><nlm:aff id="A69"> Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A71"> New York University Cancer Institute, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> New York University Cancer Institute, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Bas Bueno De Mesquita, H" sort="Bas Bueno De Mesquita, H" uniqKey="Bas Bueno De Mesquita H" first="H" last="Bas Bueno-De-Mesquita">H. Bas Bueno-De-Mesquita</name><affiliation wicri:level="3"><nlm:aff id="A72"> Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea> Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A73"> National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea> National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S" last="Fuchs">Charles S. Fuchs</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66"> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Gallinger, Steven" sort="Gallinger, Steven" uniqKey="Gallinger S" first="Steven" last="Gallinger">Steven Gallinger</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Gross, Myron D" sort="Gross, Myron D" uniqKey="Gross M" first="Myron D" last="Gross">Myron D. Gross</name><affiliation wicri:level="2"><nlm:aff id="A75"> Department of Laboratory Medicine and Pathology, School of Medicine, University of Minnesota, Minneapolis, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Laboratory Medicine and Pathology, School of Medicine, University of Minnesota, Minneapolis, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A" last="Holly">Elizabeth A. Holly</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Klein, Alison P" sort="Klein, Alison P" uniqKey="Klein A" first="Alison P" last="Klein">Alison P. Klein</name><affiliation wicri:level="2"><nlm:aff id="A77"> Department of Oncology, the Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Oncology, the Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Lacroix, Andrea" sort="Lacroix, Andrea" uniqKey="Lacroix A" first="Andrea" last="Lacroix">Andrea Lacroix</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mandelson, Margaret T" sort="Mandelson, Margaret T" uniqKey="Mandelson M" first="Margaret T" last="Mandelson">Margaret T. Mandelson</name><affiliation wicri:level="2"><nlm:aff id="A53"> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A78"> Group Health Center for Health Studies, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Group Health Center for Health Studies, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Petersen, Gloria" sort="Petersen, Gloria" uniqKey="Petersen G" first="Gloria" last="Petersen">Gloria Petersen</name><affiliation wicri:level="2"><nlm:aff id="A79"> Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name><affiliation wicri:level="1"><nlm:aff id="A80"> Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Sud University, Institut Gustave-Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea> Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Sud University, Institut Gustave-Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name><affiliation wicri:level="3"><nlm:aff id="A81"> Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea> Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Chang, Kenneth" sort="Chang, Kenneth" uniqKey="Chang K" first="Kenneth" last="Chang">Kenneth Chang</name><affiliation wicri:level="2"><nlm:aff id="A82"> Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cotterchio, Michelle" sort="Cotterchio, Michelle" uniqKey="Cotterchio M" first="Michelle" last="Cotterchio">Michelle Cotterchio</name><affiliation wicri:level="4"><nlm:aff id="A83"> Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A85"> Department of Nutrition, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Nutrition, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Goggins, Michael" sort="Goggins, Michael" uniqKey="Goggins M" first="Michael" last="Goggins">Michael Goggins</name><affiliation wicri:level="2"><nlm:aff id="A76"> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A86"> Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87"> Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bolton, Judith A Hoffman" sort="Bolton, Judith A Hoffman" uniqKey="Bolton J" first="Judith A Hoffman" last="Bolton">Judith A Hoffman Bolton</name><affiliation wicri:level="2"><nlm:aff id="A55"> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jenab, Mazda" sort="Jenab, Mazda" uniqKey="Jenab M" first="Mazda" last="Jenab">Mazda Jenab</name><affiliation wicri:level="3"><nlm:aff id="A88"> International Agency for Research on Cancer (IARC/WHO), Lyon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea> International Agency for Research on Cancer (IARC/WHO), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A89"> Department of Public Health and Primary Care, Clinical Gerontology, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Department of Public Health and Primary Care, Clinical Gerontology, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Krogh, Vittorio" sort="Krogh, Vittorio" uniqKey="Krogh V" first="Vittorio" last="Krogh">Vittorio Krogh</name><affiliation wicri:level="3"><nlm:aff id="A90"> Nutritional Epidemiology Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Nazionale dei Tumori, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea> Nutritional Epidemiology Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Nazionale dei Tumori, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Kurtz, Robert C" sort="Kurtz, Robert C" uniqKey="Kurtz R" first="Robert C" last="Kurtz">Robert C. Kurtz</name><affiliation wicri:level="2"><nlm:aff id="A91"> Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Mcwilliams, Robert R" sort="Mcwilliams, Robert R" uniqKey="Mcwilliams R" first="Robert R" last="Mcwilliams">Robert R. Mcwilliams</name><affiliation wicri:level="2"><nlm:aff id="A92"> Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Medical Oncology, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Mendelsohn, Julie B" sort="Mendelsohn, Julie B" uniqKey="Mendelsohn J" first="Julie B" last="Mendelsohn">Julie B. Mendelsohn</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rabe, Kari G" sort="Rabe, Kari G" uniqKey="Rabe K" first="Kari G" last="Rabe">Kari G. Rabe</name><affiliation wicri:level="2"><nlm:aff id="A79"> Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Health Sciences Research, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="3"><nlm:aff id="A51"> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation wicri:level="3"><nlm:aff id="A50"> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea> Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Tobias, Geoffrey S" sort="Tobias, Geoffrey S" uniqKey="Tobias G" first="Geoffrey S" last="Tobias">Geoffrey S. Tobias</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A93"> Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea> Bureau of Epidemiologic Research, Academy of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Elena, Joanne W" sort="Elena, Joanne W" uniqKey="Elena J" first="Joanne W" last="Elena">Joanne W. Elena</name><affiliation wicri:level="2"><nlm:aff id="A38"> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Clinical and Translational Epidemiology Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yu, Herbert" sort="Yu, Herbert" uniqKey="Yu H" first="Herbert" last="Yu">Herbert Yu</name><affiliation wicri:level="1"><nlm:aff id="A24"> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813</wicri:regionArea><wicri:noRegion>Hawaii 96813</wicri:noRegion></affiliation></author><author><name sortKey="Amundadottir, Laufey" sort="Amundadottir, Laufey" uniqKey="Amundadottir L" first="Laufey" last="Amundadottir">Laufey Amundadottir</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Stolzenberg Solomon, Rachael Z" sort="Stolzenberg Solomon, Rachael Z" uniqKey="Stolzenberg Solomon R" first="Rachael Z" last="Stolzenberg-Solomon">Rachael Z. Stolzenberg-Solomon</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Schumacher, Fredrick" sort="Schumacher, Fredrick" uniqKey="Schumacher F" first="Fredrick" last="Schumacher">Fredrick Schumacher</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Stram, Daniel" sort="Stram, Daniel" uniqKey="Stram D" first="Daniel" last="Stram">Daniel Stram</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Savage, Sharon A" sort="Savage, Sharon A" uniqKey="Savage S" first="Sharon A" last="Savage">Sharon A. Savage</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mirabello, Lisa" sort="Mirabello, Lisa" uniqKey="Mirabello L" first="Lisa" last="Mirabello">Lisa Mirabello</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L" last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A94"> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Wunder, Jay S" sort="Wunder, Jay S" uniqKey="Wunder J" first="Jay S" last="Wunder">Jay S. Wunder</name><affiliation wicri:level="1"><nlm:aff id="A74"> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Fred. A. Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A94"> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea> Mount Sinai Hospital Christopher Sharp Centre for Surgery and Oncology, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Ana Pati O" sort="Garcia, Ana Pati O" uniqKey="Garcia A" first="Ana Pati O" last="García">Ana Pati O García</name><affiliation wicri:level="1"><nlm:aff id="A95"> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona</wicri:regionArea><wicri:noRegion>E31080 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Sierrasesumaga, Luis" sort="Sierrasesumaga, Luis" uniqKey="Sierrasesumaga L" first="Luis" last="Sierrasesúmaga">Luis Sierrasesúmaga</name><affiliation wicri:level="1"><nlm:aff id="A95"> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Department of Pediatrics, Clínica Universidad de Navarra, E31080 Pamplona</wicri:regionArea><wicri:noRegion>E31080 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Barkauskas, Donald A" sort="Barkauskas, Donald A" uniqKey="Barkauskas D" first="Donald A" last="Barkauskas">Donald A. Barkauskas</name><affiliation wicri:level="1"><nlm:aff id="A23"> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033</wicri:regionArea><wicri:noRegion>California 90033</wicri:noRegion></affiliation></author><author><name sortKey="Gorlick, Richard G" sort="Gorlick, Richard G" uniqKey="Gorlick R" first="Richard G" last="Gorlick">Richard G. Gorlick</name><affiliation wicri:level="2"><nlm:aff id="A96"> Department of Molecular Pharmacology , Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Molecular Pharmacology , Albert Einstein College of Medicine of Yeshiva University, Bronx, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A97"> Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chow, Wong Ho" sort="Chow, Wong Ho" uniqKey="Chow W" first="Wong-Ho" last="Chow">Wong-Ho Chow</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Moore, Lee E" sort="Moore, Lee E" uniqKey="Moore L" first="Lee E" last="Moore">Lee E. Moore</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schwartz, Kendra L" sort="Schwartz, Kendra L" uniqKey="Schwartz K" first="Kendra L" last="Schwartz">Kendra L. Schwartz</name><affiliation wicri:level="2"><nlm:aff id="A98"> Department of Family Medicine and Public Health Sciences, Wayne State University, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Family Medicine and Public Health Sciences, Wayne State University, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Davis, Faith G" sort="Davis, Faith G" uniqKey="Davis F" first="Faith G" last="Davis">Faith G. Davis</name><affiliation wicri:level="4"><nlm:aff id="A99"> Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region><settlement type="city">Chicago</settlement></placeName><orgName type="university">Université de l'Illinois à Chicago</orgName></affiliation></author><author><name sortKey="Hsing, Ann W" sort="Hsing, Ann W" uniqKey="Hsing A" first="Ann W" last="Hsing">Ann W. Hsing</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Black, Amanda" sort="Black, Amanda" uniqKey="Black A" first="Amanda" last="Black">Amanda Black</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Wentzensen, Nicolas" sort="Wentzensen, Nicolas" uniqKey="Wentzensen N" first="Nicolas" last="Wentzensen">Nicolas Wentzensen</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A" last="Brinton">Louise A. Brinton</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name><affiliation wicri:level="1"><nlm:aff id="A100"> Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea> Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Peplonska, Beata" sort="Peplonska, Beata" uniqKey="Peplonska B" first="Beata" last="Peplonska">Beata Peplonska</name><affiliation wicri:level="1"><nlm:aff id="A101"> Nofer Institute of Occupational Medicine, Lodz, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea> Nofer Institute of Occupational Medicine, Lodz</wicri:regionArea><wicri:noRegion>Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Mcglynn, Katherine A" sort="Mcglynn, Katherine A" uniqKey="Mcglynn K" first="Katherine A" last="Mcglynn">Katherine A. Mcglynn</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Cook, Michael B" sort="Cook, Michael B" uniqKey="Cook M" first="Michael B" last="Cook">Michael B. Cook</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Graubard, Barry I" sort="Graubard, Barry I" uniqKey="Graubard B" first="Barry I" last="Graubard">Barry I. Graubard</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kratz, Christian P" sort="Kratz, Christian P" uniqKey="Kratz C" first="Christian P" last="Kratz">Christian P. Kratz</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A102"> Zentrum für Kinderheilkunde und Jugendmedizin, Klinik für Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea> Zentrum für Kinderheilkunde und Jugendmedizin, Klinik für Pädiatrische Hämatologie und Onkologie, Medizinische Hochschule Hannover, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Erickson, Ralph L" sort="Erickson, Ralph L" uniqKey="Erickson R" first="Ralph L" last="Erickson">Ralph L. Erickson</name><affiliation wicri:level="2"><nlm:aff id="A103"> Walter Reed Army Institute of Research, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Walter Reed Army Institute of Research, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A48"> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A84"> Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Epidemiology, Harvard School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Thomas, Gilles" sort="Thomas, Gilles" uniqKey="Thomas G" first="Gilles" last="Thomas">Gilles Thomas</name><affiliation wicri:level="2"><nlm:aff id="A103"> Walter Reed Army Institute of Research, Silver Spring, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Walter Reed Army Institute of Research, Silver Spring, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hoover, Robert N" sort="Hoover, Robert N" uniqKey="Hoover R" first="Robert N" last="Hoover">Robert N. Hoover</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Real, Francisco X" sort="Real, Francisco X" uniqKey="Real F" first="Francisco X" last="Real">Francisco X. Real</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A105"> Epithelial Carcinogenesis Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Epithelial Carcinogenesis Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F" last="Fraumeni">Joseph F. Fraumeni</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Caporaso, Neil E" sort="Caporaso, Neil E" uniqKey="Caporaso N" first="Neil E" last="Caporaso">Neil E. Caporaso</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Tucker, Margaret" sort="Tucker, Margaret" uniqKey="Tucker M" first="Margaret" last="Tucker">Margaret Tucker</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Perez Jurado, Luis A" sort="Perez Jurado, Luis A" uniqKey="Perez Jurado L" first="Luis A" last="Pérez-Jurado">Luis A. Pérez-Jurado</name><affiliation wicri:level="4"><nlm:aff id="A3"> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona</wicri:regionArea><orgName type="university">Université Pompeu Fabra</orgName><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A4"> Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), E-08003 Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), E-08003 Barcelona</wicri:regionArea><wicri:noRegion>E-08003 Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><nlm:aff id="A1"> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P2">In an analysis of 31,717 cancer cases and 26,136 cancer-free controls drawn from 13 genome-wide association studies (GWAS), we observed large chromosomal abnormalities in a subset of clones from DNA obtained from blood or buccal samples. Mosaic chromosomal abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of size >2 Mb were observed in autosomes of 517 individuals (0.89%) with abnormal cell proportions between 7% and 95%. In cancer-free individuals, the frequency increased with age; 0.23% under 50 and 1.91% between 75 and 79 (p=4.8×10<sup>−8</sup>). Mosaic abnormalities were more frequent in individuals with solid-tumors (0.97% versus 0.74% in cancer-free individuals, OR=1.25, p=0.016), with a stronger association for cases who had DNA collected prior to diagnosis or treatment (OR=1.45, p=0.0005). Detectable clonal mosaicism was common in individuals for whom DNA was collected at least one year prior to diagnosis of leukemia compared to cancer-free individuals (OR=35.4, p=3.8×10<sup>−11</sup>). These findings underscore the importance of the role and time-dependent nature of somatic events in the etiology of cancer and other late-onset diseases.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Youssoufian, H" uniqKey="Youssoufian H">H Youssoufian</name></author><author><name sortKey="Pyeritz, Re" uniqKey="Pyeritz R">RE Pyeritz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Notini, Aj" uniqKey="Notini A">AJ Notini</name></author><author><name sortKey="Craig, Jm" uniqKey="Craig J">JM Craig</name></author><author><name sortKey="White, Sj" uniqKey="White S">SJ White</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, Ly" uniqKey="Hsu L">LY Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menten, B" uniqKey="Menten B">B Menten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, 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(État)</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Minnesota</li><li>Ohio</li><li>Ontario</li><li>Pennsylvanie</li><li>Rhode Island</li><li>Rhône-Alpes</li><li>Svealand</li><li>Tennessee</li><li>Texas</li><li>Utrecht (province)</li><li>Vermont</li><li>Victoria (État)</li><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Athènes</li><li>Barcelone</li><li>Cambridge</li><li>Chicago</li><li>Copenhague</li><li>Hanovre</li><li>Heidelberg</li><li>Londres</li><li>Lyon</li><li>Madrid</li><li>Melbourne</li><li>Milan</li><li>Providence (Rhode Island)</li><li>Pékin</li><li>Seattle</li><li>Stockholm</li><li>Toronto</li><li>Utrecht</li></settlement><orgName><li>Université Brown</li><li>Université Pompeu Fabra</li><li>Université de Cambridge</li><li>Université de Melbourne</li><li>Université de Toronto</li><li>Université de Washington</li><li>Université de l'Illinois à Chicago</li><li>Université nationale de Singapour</li></orgName></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B" last="Jacobs">Kevin B. Jacobs</name></region><name sortKey="Abnet, Christian C" sort="Abnet, Christian C" uniqKey="Abnet C" first="Christian C" last="Abnet">Christian C. Abnet</name><name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><name sortKey="Aldrich, Melinda C" sort="Aldrich, Melinda C" uniqKey="Aldrich M" first="Melinda C" last="Aldrich">Melinda C. Aldrich</name><name sortKey="Amos, Christopher" sort="Amos, Christopher" uniqKey="Amos C" first="Christopher" last="Amos">Christopher Amos</name><name sortKey="Amundadottir, Laufey" sort="Amundadottir, Laufey" uniqKey="Amundadottir L" first="Laufey" last="Amundadottir">Laufey Amundadottir</name><name sortKey="Arslan, Alan A" sort="Arslan, Alan A" uniqKey="Arslan A" first="Alan A" last="Arslan">Alan A. Arslan</name><name sortKey="Arslan, Alan A" sort="Arslan, Alan A" uniqKey="Arslan A" first="Alan A" last="Arslan">Alan A. Arslan</name><name sortKey="Baris, Dalsu" sort="Baris, Dalsu" uniqKey="Baris D" first="Dalsu" last="Baris">Dalsu Baris</name><name sortKey="Barkauskas, Donald A" sort="Barkauskas, Donald A" uniqKey="Barkauskas D" first="Donald A" last="Barkauskas">Donald A. Barkauskas</name><name sortKey="Berg, Christine D" sort="Berg, Christine D" uniqKey="Berg C" first="Christine D" last="Berg">Christine D. Berg</name><name sortKey="Berndt, Sonja I" sort="Berndt, Sonja I" uniqKey="Berndt S" first="Sonja I" last="Berndt">Sonja I. Berndt</name><name sortKey="Black, Amanda" sort="Black, Amanda" uniqKey="Black A" first="Amanda" last="Black">Amanda Black</name><name sortKey="Blot, William J" sort="Blot, William J" uniqKey="Blot W" first="William J" last="Blot">William J. Blot</name><name sortKey="Blot, William J" sort="Blot, William J" uniqKey="Blot W" first="William J" last="Blot">William J. Blot</name><name sortKey="Bock, Cathryn H" sort="Bock, Cathryn H" uniqKey="Bock C" first="Cathryn H" last="Bock">Cathryn H. Bock</name><name sortKey="Bock, Cathryn H" sort="Bock, Cathryn H" uniqKey="Bock C" first="Cathryn H" last="Bock">Cathryn H. Bock</name><name sortKey="Bolton, Judith A Hoffman" sort="Bolton, Judith A Hoffman" uniqKey="Bolton J" first="Judith A Hoffman" last="Bolton">Judith A Hoffman Bolton</name><name sortKey="Bracci, Paige M" sort="Bracci, Paige M" uniqKey="Bracci P" first="Paige M" last="Bracci">Paige M. Bracci</name><name sortKey="Brinton, Louise A" sort="Brinton, Louise A" uniqKey="Brinton L" first="Louise A" last="Brinton">Louise A. Brinton</name><name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name><name sortKey="Burdett, Laurie" sort="Burdett, Laurie" uniqKey="Burdett L" first="Laurie" last="Burdett">Laurie Burdett</name><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E" last="Buring">Julie E. Buring</name><name sortKey="Butler, Mary A" sort="Butler, Mary A" uniqKey="Butler M" first="Mary A" last="Butler">Mary A. Butler</name><name sortKey="Caporaso, Neil E" sort="Caporaso, Neil E" uniqKey="Caporaso N" first="Neil E" last="Caporaso">Neil E. Caporaso</name><name sortKey="Carreon, Tania" sort="Carreon, Tania" uniqKey="Carreon T" first="Tania" last="Carreon">Tania Carreon</name><name sortKey="Chang, Kenneth" sort="Chang, Kenneth" uniqKey="Chang K" first="Kenneth" last="Chang">Kenneth Chang</name><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J" last="Chanock">Stephen J. Chanock</name><name sortKey="Chatterjee, Nilanjan" sort="Chatterjee, Nilanjan" uniqKey="Chatterjee N" first="Nilanjan" last="Chatterjee">Nilanjan Chatterjee</name><name sortKey="Chow, Wong Ho" sort="Chow, Wong Ho" uniqKey="Chow W" first="Wong-Ho" last="Chow">Wong-Ho Chow</name><name sortKey="Chung, Charles C" sort="Chung, Charles C" uniqKey="Chung C" first="Charles C" last="Chung">Charles C. Chung</name><name sortKey="Cook, Michael B" sort="Cook, Michael B" uniqKey="Cook M" first="Michael B" last="Cook">Michael B. Cook</name><name sortKey="Cullen, Michael" sort="Cullen, Michael" uniqKey="Cullen M" first="Michael" last="Cullen">Michael Cullen</name><name sortKey="Cullen, Michael" sort="Cullen, Michael" uniqKey="Cullen M" first="Michael" last="Cullen">Michael Cullen</name><name sortKey="Davis, Faith G" sort="Davis, Faith G" uniqKey="Davis F" first="Faith G" last="Davis">Faith G. Davis</name><name sortKey="Dean, Michael C" sort="Dean, Michael C" uniqKey="Dean M" first="Michael C" last="Dean">Michael C. Dean</name><name sortKey="Deng, Xiang" sort="Deng, Xiang" uniqKey="Deng X" first="Xiang" last="Deng">Xiang Deng</name><name sortKey="Deng, Xiang" sort="Deng, Xiang" uniqKey="Deng X" first="Xiang" last="Deng">Xiang Deng</name><name sortKey="Elena, Joanne W" sort="Elena, Joanne W" uniqKey="Elena J" first="Joanne W" last="Elena">Joanne W. Elena</name><name sortKey="Epstein, Caroline G" sort="Epstein, Caroline G" uniqKey="Epstein C" first="Caroline G" last="Epstein">Caroline G. Epstein</name><name sortKey="Erickson, Ralph L" sort="Erickson, Ralph L" uniqKey="Erickson R" first="Ralph L" last="Erickson">Ralph L. Erickson</name><name sortKey="Figueroa, Jonine D" sort="Figueroa, Jonine D" uniqKey="Figueroa J" first="Jonine D" last="Figueroa">Jonine D. Figueroa</name><name sortKey="Fraumeni, Joseph F" sort="Fraumeni, Joseph F" uniqKey="Fraumeni J" first="Joseph F" last="Fraumeni">Joseph F. Fraumeni</name><name sortKey="Freedman, Neal D" sort="Freedman, Neal D" uniqKey="Freedman N" first="Neal D" last="Freedman">Neal D. Freedman</name><name sortKey="Freeman, Laura E Beane" sort="Freeman, Laura E Beane" uniqKey="Freeman L" first="Laura E Beane" last="Freeman">Laura E Beane Freeman</name><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S" last="Fuchs">Charles S. Fuchs</name><name sortKey="Fuchs, Charles S" sort="Fuchs, Charles S" uniqKey="Fuchs C" first="Charles S" last="Fuchs">Charles S. Fuchs</name><name sortKey="Gapstur, Susan M" sort="Gapstur, Susan M" uniqKey="Gapstur S" first="Susan M" last="Gapstur">Susan M. Gapstur</name><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="Garcia-Closas">Montserrat Garcia-Closas</name><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M" last="Gaudet">Mia M. Gaudet</name><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J Michael" last="Gaziano">J Michael Gaziano</name><name sortKey="Gillanders, Elizabeth M" sort="Gillanders, Elizabeth M" uniqKey="Gillanders E" first="Elizabeth M" last="Gillanders">Elizabeth M. Gillanders</name><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name><name sortKey="Giovannucci, Edward L" sort="Giovannucci, Edward L" uniqKey="Giovannucci E" first="Edward L" last="Giovannucci">Edward L. Giovannucci</name><name sortKey="Goggins, Michael" sort="Goggins, Michael" uniqKey="Goggins M" first="Michael" last="Goggins">Michael Goggins</name><name sortKey="Goggins, Michael" sort="Goggins, Michael" uniqKey="Goggins M" first="Michael" last="Goggins">Michael Goggins</name><name sortKey="Goggins, Michael" sort="Goggins, Michael" uniqKey="Goggins M" first="Michael" last="Goggins">Michael Goggins</name><name sortKey="Goldin, Lynn" sort="Goldin, Lynn" uniqKey="Goldin L" first="Lynn" last="Goldin">Lynn Goldin</name><name sortKey="Goldstein, Alisa M" sort="Goldstein, Alisa M" uniqKey="Goldstein A" first="Alisa M" last="Goldstein">Alisa M. Goldstein</name><name sortKey="Gorlick, Richard G" sort="Gorlick, Richard G" uniqKey="Gorlick R" first="Richard G" last="Gorlick">Richard G. Gorlick</name><name sortKey="Gorlick, Richard G" sort="Gorlick, Richard G" uniqKey="Gorlick R" first="Richard G" last="Gorlick">Richard G. Gorlick</name><name sortKey="Graubard, Barry I" sort="Graubard, Barry I" uniqKey="Graubard B" first="Barry I" last="Graubard">Barry I. Graubard</name><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H" last="Greene">Mark H. Greene</name><name sortKey="Gross, Myron D" sort="Gross, Myron D" uniqKey="Gross M" first="Myron D" last="Gross">Myron D. Gross</name><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A" last="Haiman">Christopher A. Haiman</name><name sortKey="Hankinson, Susan E" sort="Hankinson, Susan E" uniqKey="Hankinson S" first="Susan E" last="Hankinson">Susan E. Hankinson</name><name sortKey="Harris, Curtis C" sort="Harris, Curtis C" uniqKey="Harris C" first="Curtis C" last="Harris">Curtis C. Harris</name><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><name sortKey="Hassan, Manal" sort="Hassan, Manal" uniqKey="Hassan M" first="Manal" last="Hassan">Manal Hassan</name><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E" last="Henderson">Brian E. Henderson</name><name sortKey="Holly, Elizabeth A" sort="Holly, Elizabeth A" uniqKey="Holly E" first="Elizabeth A" last="Holly">Elizabeth A. Holly</name><name sortKey="Hoover, Robert N" sort="Hoover, Robert N" uniqKey="Hoover R" first="Robert N" last="Hoover">Robert N. Hoover</name><name sortKey="Horner, Marie Josephe" sort="Horner, Marie Josephe" uniqKey="Horner M" first="Marie-Josephe" last="Horner">Marie-Josephe Horner</name><name sortKey="Hsing, Ann W" sort="Hsing, Ann W" uniqKey="Hsing A" first="Ann W" last="Hsing">Ann W. Hsing</name><name sortKey="Hu, Nan" sort="Hu, Nan" uniqKey="Hu N" first="Nan" last="Hu">Nan Hu</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name><name sortKey="Hutchinson, Amy" sort="Hutchinson, Amy" uniqKey="Hutchinson A" first="Amy" last="Hutchinson">Amy Hutchinson</name><name sortKey="Inskip, Peter D" sort="Inskip, Peter D" uniqKey="Inskip P" first="Peter D" last="Inskip">Peter D. Inskip</name><name sortKey="Jacobs, Kevin B" sort="Jacobs, Kevin B" uniqKey="Jacobs K" first="Kevin B" last="Jacobs">Kevin B. Jacobs</name><name sortKey="Jiao, Li" sort="Jiao, Li" uniqKey="Jiao L" first="Li" last="Jiao">Li Jiao</name><name sortKey="Johnson, Alison" sort="Johnson, Alison" uniqKey="Johnson A" first="Alison" last="Johnson">Alison Johnson</name><name sortKey="Klein, Alison P" sort="Klein, Alison P" uniqKey="Klein A" first="Alison P" last="Klein">Alison P. Klein</name><name sortKey="Kolonel, Laurence N" sort="Kolonel, Laurence N" uniqKey="Kolonel L" first="Laurence N" last="Kolonel">Laurence N. Kolonel</name><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><name sortKey="Kovaks, Joseph" sort="Kovaks, Joseph" uniqKey="Kovaks J" first="Joseph" last="Kovaks">Joseph Kovaks</name><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><name sortKey="Kratz, Christian P" sort="Kratz, Christian P" uniqKey="Kratz C" first="Christian P" last="Kratz">Christian P. Kratz</name><name sortKey="Kurtz, Robert C" sort="Kurtz, Robert C" uniqKey="Kurtz R" first="Robert C" last="Kurtz">Robert C. Kurtz</name><name sortKey="Lacroix, Andrea" sort="Lacroix, Andrea" uniqKey="Lacroix A" first="Andrea" last="Lacroix">Andrea Lacroix</name><name sortKey="Landgren, Annelie" sort="Landgren, Annelie" uniqKey="Landgren A" first="Annelie" last="Landgren">Annelie Landgren</name><name sortKey="Landi, Maria Teresa" sort="Landi, Maria Teresa" uniqKey="Landi M" first="Maria Teresa" last="Landi">Maria Teresa Landi</name><name sortKey="Le Marchand, Loic" sort="Le Marchand, Loic" uniqKey="Le Marchand L" first="Loic" last="Le Marchand">Loic Le Marchand</name><name sortKey="Li, Donghui" sort="Li, Donghui" uniqKey="Li D" first="Donghui" last="Li">Donghui Li</name><name sortKey="Liao, Linda" sort="Liao, Linda" uniqKey="Liao L" first="Linda" last="Liao">Linda Liao</name><name sortKey="Liu, Chenwei" sort="Liu, Chenwei" uniqKey="Liu C" first="Chenwei" last="Liu">Chenwei Liu</name><name sortKey="Liu, Chenwei" sort="Liu, Chenwei" uniqKey="Liu C" first="Chenwei" last="Liu">Chenwei Liu</name><name sortKey="Mandelson, Margaret T" sort="Mandelson, Margaret T" uniqKey="Mandelson M" first="Margaret T" last="Mandelson">Margaret T. Mandelson</name><name sortKey="Mandelson, Margaret T" sort="Mandelson, Margaret T" uniqKey="Mandelson M" first="Margaret T" last="Mandelson">Margaret T. Mandelson</name><name sortKey="Mcglynn, Katherine A" sort="Mcglynn, Katherine A" uniqKey="Mcglynn K" first="Katherine A" last="Mcglynn">Katherine A. Mcglynn</name><name sortKey="Mckean Cowdin, Roberta" sort="Mckean Cowdin, Roberta" uniqKey="Mckean Cowdin R" first="Roberta" last="Mckean-Cowdin">Roberta Mckean-Cowdin</name><name sortKey="Mcneill, Lorna H" sort="Mcneill, Lorna H" uniqKey="Mcneill L" first="Lorna H" last="Mcneill">Lorna H. Mcneill</name><name sortKey="Mcneill, Lorna H" sort="Mcneill, Lorna H" uniqKey="Mcneill L" first="Lorna H" last="Mcneill">Lorna H. Mcneill</name><name sortKey="Mcwilliams, Robert R" sort="Mcwilliams, Robert R" uniqKey="Mcwilliams R" first="Robert R" last="Mcwilliams">Robert R. Mcwilliams</name><name sortKey="Mendelsohn, Julie B" sort="Mendelsohn, Julie B" uniqKey="Mendelsohn J" first="Julie B" last="Mendelsohn">Julie B. Mendelsohn</name><name sortKey="Michaud, Dominique S" sort="Michaud, Dominique S" uniqKey="Michaud D" first="Dominique S" last="Michaud">Dominique S. Michaud</name><name sortKey="Mirabello, Lisa" sort="Mirabello, Lisa" uniqKey="Mirabello L" first="Lisa" last="Mirabello">Lisa Mirabello</name><name sortKey="Moore, Lee E" sort="Moore, Lee E" uniqKey="Moore L" first="Lee E" last="Moore">Lee E. Moore</name><name sortKey="Olson, Sara H" sort="Olson, Sara H" uniqKey="Olson S" first="Sara H" last="Olson">Sara H. Olson</name><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><name sortKey="Petersen, Gloria" sort="Petersen, Gloria" uniqKey="Petersen G" first="Gloria" last="Petersen">Gloria Petersen</name><name sortKey="Prokunina Olsson, Ludmila" sort="Prokunina Olsson, Ludmila" uniqKey="Prokunina Olsson L" first="Ludmila" last="Prokunina-Olsson">Ludmila Prokunina-Olsson</name><name sortKey="Purdue, Mark" sort="Purdue, Mark" uniqKey="Purdue M" first="Mark" last="Purdue">Mark Purdue</name><name sortKey="Rabe, Kari G" sort="Rabe, Kari G" uniqKey="Rabe K" first="Kari G" last="Rabe">Kari G. Rabe</name><name sortKey="Rajaraman, Preetha" sort="Rajaraman, Preetha" uniqKey="Rajaraman P" first="Preetha" last="Rajaraman">Preetha Rajaraman</name><name sortKey="Risch, Harvey A" sort="Risch, Harvey A" uniqKey="Risch H" first="Harvey A" last="Risch">Harvey A. Risch</name><name sortKey="Rothman, Nathaniel" sort="Rothman, Nathaniel" uniqKey="Rothman N" first="Nathaniel" last="Rothman">Nathaniel Rothman</name><name sortKey="Rotunno, Melissa" sort="Rotunno, Melissa" uniqKey="Rotunno M" first="Melissa" last="Rotunno">Melissa Rotunno</name><name sortKey="Ruder, Avima M" sort="Ruder, Avima M" uniqKey="Ruder A" first="Avima M" last="Ruder">Avima M. Ruder</name><name sortKey="Rybicki, Benjamin A" sort="Rybicki, Benjamin A" uniqKey="Rybicki B" first="Benjamin A" last="Rybicki">Benjamin A. Rybicki</name><name sortKey="Sampson, Joshua" sort="Sampson, Joshua" uniqKey="Sampson J" first="Joshua" last="Sampson">Joshua Sampson</name><name sortKey="Savage, Sharon A" sort="Savage, Sharon A" uniqKey="Savage S" first="Sharon A" last="Savage">Sharon A. Savage</name><name sortKey="Schumacher, Fredrick" sort="Schumacher, Fredrick" uniqKey="Schumacher F" first="Fredrick" last="Schumacher">Fredrick Schumacher</name><name sortKey="Schwartz, Ann G" sort="Schwartz, Ann G" uniqKey="Schwartz A" first="Ann G" last="Schwartz">Ann G. Schwartz</name><name sortKey="Schwartz, Ann G" sort="Schwartz, Ann G" uniqKey="Schwartz A" first="Ann G" last="Schwartz">Ann G. Schwartz</name><name sortKey="Schwartz, Kendra L" sort="Schwartz, Kendra L" uniqKey="Schwartz K" first="Kendra L" last="Schwartz">Kendra L. Schwartz</name><name sortKey="Schwenn, Molly" sort="Schwenn, Molly" uniqKey="Schwenn M" first="Molly" last="Schwenn">Molly Schwenn</name><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D" last="Sesso">Howard D. Sesso</name><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><name sortKey="Signorello, Lisa B" sort="Signorello, Lisa B" uniqKey="Signorello L" first="Lisa B" last="Signorello">Lisa B. Signorello</name><name sortKey="Signorello, Lisa B" sort="Signorello, Lisa B" uniqKey="Signorello L" first="Lisa B" last="Signorello">Lisa B. Signorello</name><name sortKey="Signorello, Lisa B" sort="Signorello, Lisa B" uniqKey="Signorello L" first="Lisa B" last="Signorello">Lisa B. Signorello</name><name sortKey="Silverman, Debra T" sort="Silverman, Debra T" uniqKey="Silverman D" first="Debra T" last="Silverman">Debra T. Silverman</name><name sortKey="Spitz, Margaret R" sort="Spitz, Margaret R" uniqKey="Spitz M" first="Margaret R" last="Spitz">Margaret R. Spitz</name><name sortKey="Stevens, Victoria L" sort="Stevens, Victoria L" uniqKey="Stevens V" first="Victoria L" last="Stevens">Victoria L. Stevens</name><name sortKey="Stolzenberg Solomon, Rachael Z" sort="Stolzenberg Solomon, Rachael Z" uniqKey="Stolzenberg Solomon R" first="Rachael Z" last="Stolzenberg-Solomon">Rachael Z. Stolzenberg-Solomon</name><name sortKey="Stram, Daniel" sort="Stram, Daniel" uniqKey="Stram D" first="Daniel" last="Stram">Daniel Stram</name><name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name><name sortKey="Teras, Lauren T" sort="Teras, Lauren T" uniqKey="Teras L" first="Lauren T" last="Teras">Lauren T. Teras</name><name sortKey="Thomas, Gilles" sort="Thomas, Gilles" uniqKey="Thomas G" first="Gilles" last="Thomas">Gilles Thomas</name><name sortKey="Tobias, Geoffrey S" sort="Tobias, Geoffrey S" uniqKey="Tobias G" first="Geoffrey S" last="Tobias">Geoffrey S. Tobias</name><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><name sortKey="Tucker, Margaret" sort="Tucker, Margaret" uniqKey="Tucker M" first="Margaret" last="Tucker">Margaret Tucker</name><name sortKey="Visvanathan, Kala" sort="Visvanathan, Kala" uniqKey="Visvanathan K" first="Kala" last="Visvanathan">Kala Visvanathan</name><name sortKey="Wacholder, Sholom" sort="Wacholder, Sholom" uniqKey="Wacholder S" first="Sholom" last="Wacholder">Sholom Wacholder</name><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><name sortKey="Wang, Zhaoming" sort="Wang, Zhaoming" uniqKey="Wang Z" first="Zhaoming" last="Wang">Zhaoming Wang</name><name sortKey="Weinstein, Stephanie J" sort="Weinstein, Stephanie J" uniqKey="Weinstein S" first="Stephanie J" last="Weinstein">Stephanie J. Weinstein</name><name sortKey="Wentzensen, Nicolas" sort="Wentzensen, Nicolas" uniqKey="Wentzensen N" first="Nicolas" last="Wentzensen">Nicolas Wentzensen</name><name sortKey="Wheeler, William" sort="Wheeler, William" uniqKey="Wheeler W" first="William" last="Wheeler">William Wheeler</name><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><name sortKey="Wiencke, John K" sort="Wiencke, John K" uniqKey="Wiencke J" first="John K" last="Wiencke">John K. Wiencke</name><name sortKey="Wolpin, Brian M" sort="Wolpin, Brian M" uniqKey="Wolpin B" first="Brian M" last="Wolpin">Brian M. Wolpin</name><name sortKey="Wolpin, Brian M" sort="Wolpin, Brian M" uniqKey="Wolpin B" first="Brian M" last="Wolpin">Brian M. Wolpin</name><name sortKey="Wrensch, Margaret" sort="Wrensch, Margaret" uniqKey="Wrensch M" first="Margaret" last="Wrensch">Margaret Wrensch</name><name sortKey="Wu, Xifeng" sort="Wu, Xifeng" uniqKey="Wu X" first="Xifeng" last="Wu">Xifeng Wu</name><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><name sortKey="Yeager, Meredith" sort="Yeager, Meredith" uniqKey="Yeager M" first="Meredith" last="Yeager">Meredith Yeager</name><name sortKey="Yu, Herbert" sort="Yu, Herbert" uniqKey="Yu H" first="Herbert" last="Yu">Herbert Yu</name><name sortKey="Yu, Kai" sort="Yu, Kai" uniqKey="Yu K" first="Kai" last="Yu">Kai Yu</name><name sortKey="Yuan, Jian Min" sort="Yuan, Jian Min" uniqKey="Yuan J" first="Jian-Min" last="Yuan">Jian-Min Yuan</name><name sortKey="Yuan, Jian Min" sort="Yuan, Jian Min" uniqKey="Yuan J" first="Jian-Min" last="Yuan">Jian-Min Yuan</name><name sortKey="Zanetti, Krista A" sort="Zanetti, Krista A" uniqKey="Zanetti K" first="Krista A" last="Zanetti">Krista A. Zanetti</name><name sortKey="Zanetti, Krista A" sort="Zanetti, Krista A" uniqKey="Zanetti K" first="Krista A" last="Zanetti">Krista A. Zanetti</name><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><name sortKey="Zhou, Weiyin" sort="Zhou, Weiyin" uniqKey="Zhou W" first="Weiyin" last="Zhou">Weiyin Zhou</name><name sortKey="Zhou, Weiyin" sort="Zhou, Weiyin" uniqKey="Zhou W" first="Weiyin" last="Zhou">Weiyin Zhou</name><name sortKey="Ziegler, Regina G" sort="Ziegler, Regina G" uniqKey="Ziegler R" first="Regina G" last="Ziegler">Regina G. Ziegler</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Rodriguez Santiago, Benjamin" sort="Rodriguez Santiago, Benjamin" uniqKey="Rodriguez Santiago B" first="Benjamin" last="Rodriguez-Santiago">Benjamin Rodriguez-Santiago</name></region><name sortKey="Duell, Eric J" sort="Duell, Eric J" uniqKey="Duell E" first="Eric J" last="Duell">Eric J. Duell</name><name sortKey="Garcia, Ana Pati O" sort="Garcia, Ana Pati O" uniqKey="Garcia A" first="Ana Pati O" last="García">Ana Pati O García</name><name sortKey="Gonzalez, Juan R" sort="Gonzalez, Juan R" uniqKey="Gonzalez J" first="Juan R" last="Gonzalez">Juan R. Gonzalez</name><name sortKey="Gonzalez, Juan R" sort="Gonzalez, Juan R" uniqKey="Gonzalez J" first="Juan R" last="Gonzalez">Juan R. Gonzalez</name><name sortKey="Kogevinas, Manolis" sort="Kogevinas, Manolis" uniqKey="Kogevinas M" first="Manolis" last="Kogevinas">Manolis Kogevinas</name><name sortKey="Malats, Nuria" sort="Malats, Nuria" uniqKey="Malats N" first="Nuria" last="Malats">Nuria Malats</name><name sortKey="Marenne, Gaelle" sort="Marenne, Gaelle" uniqKey="Marenne G" first="Gaelle" last="Marenne">Gaelle Marenne</name><name sortKey="Perez Jurado, Luis A" sort="Perez Jurado, Luis A" uniqKey="Perez Jurado L" first="Luis A" last="Pérez-Jurado">Luis A. Pérez-Jurado</name><name sortKey="Perez Jurado, Luis A" sort="Perez Jurado, Luis A" uniqKey="Perez Jurado L" first="Luis A" last="Pérez-Jurado">Luis A. Pérez-Jurado</name><name sortKey="Real, Francisco X" sort="Real, Francisco X" uniqKey="Real F" first="Francisco X" last="Real">Francisco X. Real</name><name sortKey="Real, Francisco X" sort="Real, Francisco X" uniqKey="Real F" first="Francisco X" last="Real">Francisco X. 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Wunder</name><name sortKey="Wunder, Jay S" sort="Wunder, Jay S" uniqKey="Wunder J" first="Jay S" last="Wunder">Jay S. Wunder</name></country><country name="France"><noRegion><name sortKey="Boutron Ruault, Marie Christine" sort="Boutron Ruault, Marie Christine" uniqKey="Boutron Ruault M" first="Marie-Christine" last="Boutron-Ruault">Marie-Christine Boutron-Ruault</name></noRegion><name sortKey="Jenab, Mazda" sort="Jenab, Mazda" uniqKey="Jenab M" first="Mazda" last="Jenab">Mazda Jenab</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Canzian, Federico" sort="Canzian, Federico" uniqKey="Canzian F" first="Federico" last="Canzian">Federico Canzian</name></region><name sortKey="Kratz, Christian P" sort="Kratz, Christian P" uniqKey="Kratz C" first="Christian P" last="Kratz">Christian P. Kratz</name></country><country name="Pologne"><noRegion><name sortKey="Lissowska, Jolanta" sort="Lissowska, Jolanta" uniqKey="Lissowska J" first="Jolanta" last="Lissowska">Jolanta Lissowska</name></noRegion><name sortKey="Peplonska, Beata" sort="Peplonska, Beata" uniqKey="Peplonska B" first="Beata" last="Peplonska">Beata Peplonska</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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